The frequent occurrence of genital herpes continues to be a serious clinical problem. Although not life threatening, the physical symptoms of the disease, and the ensuing psychosocial complications, can be overwhelming to patients. The life cycle of the herpes simplex virus is complex, comprising multiple stages. Following infection, the virus establishes life-long latency in its host and can r...

INTRODUCTION Worldwide, about 90% of people are infected with the herpes simplex virus, 30% of whom will experience recurrent herpes simplex labialis, commonly referred to as 'cold sores', which can last up to 10 days. The most common treatment is aciclovir cream which reduces healing time by just half a day compared with no specific treatment. This is a protocol for a randomised controlled tri...

Background: Herpes Simplex Virus type 2 (HSV-2) infection can caused genital herpes with a high recurrence rate. Recurrent affects patients' quality of life and needs rapid treatment.
 Case presentation: This study reported 34 years old male recurrent herpes. The patient developed painful vesicles in the area, which turned into an ulcer. History gonorrhoea urethritis were had been treated....

Striae distensae: Are scars on the skin that have an atrophic linear depression, produced by stretching of skin. Causes include puberty, pregnancy, mechanical stress, hormonal, genetic role and cachectic states medications. Treatment occurred enhancing collagen production or reducing vascularity. Micro needling (MN) is a modern therapeutic option in dermatology. MN instruments automated micro d...

BACKGROUND Recent research has shown that low-level light therapy (LLLT) using 1072 nm infrared light is effective in reducing the duration of herpes simplex labialis (HSL) episodes and enhancing the healing process. METHODS This was a prospective, randomized, placebo-controlled, clinical trial to evaluate the efficacy of a 1072 nm light-emitting diode device for the treatment of HSL. In tota...

Over the past 12 years there have been no new drugs licenced for the treatment of uncomplicated genital herpes (GH) infection. What clinicians have instead seen is a refinement in the doses of the various agents used and an extension of these therapies into areas of management of herpes simplex virus (HSV) that were hitherto unexpected. Sentinel studies have not just defined the benefits of the...

The ethanol extract of Gynura procumbens showed virucidal and antireplicative actions against herpes simplex virus HSV-1 and HSV-2. It was further chromatographed on MCI gel CHP20P column giving the extract fractions F1 (water), F2 (water-methanol) F3 (methanol), and F4 (ethyl acetate). All but F1 had virucidal action against both viral types. We reported here the active compounds from F2 and F...

Both viral and host genetics affect the outcome of herpes simplex virus type 1 (HSV-1) infection in humans and experimental models. Little is known about specific host gene variants and molecular networks that influence herpetic disease progression, severity, and episodic reactivation. To identify such host gene variants we have initiated a forward genetic analysis using the expanded family of ...