hyper igm syndrome (him sx) is a rare congenital primary immunodeficiency that affects males more than females (70%, x-iinked recessive), but there are reports of autosomal recessive and autosomal dominant inheritances. in this study, we review medical histories of 2 affected girls and one affected boy. our 3 cases fulfill clinical and laboratory criteria of this syndrome. their clinical signs ...

BACKGROUND The role of contact allergy in oral cavity disease processes is unknown. OBJECTIVE We sought to determine the prevalence of contact allergy to flavorings, preservatives, dental acrylates, medications, and metals in patients with oral disease. METHODS Patients were tested with an 85-item oral antigen screening series. Data were analyzed retrospectively. RESULTS We evaluated 331 ...

Among 40 children undergoing tonsillectomy for recurrent pharyngitis, 15 (37.5%) had presented preoperatively with complaints compatible with PFAPA syndrome. All 15 had had periodic fever every three to four weeks and pharyngitis; 12 (80%) had cervical adenitis and five (33%) aphthous stomatitis. All children had been well between episodes and showed a dramatic postoperative improvement. PFAPA ...

The buccal mucosa of 30 patients with recurrent aphthous stomatitis and 15 healthy controls was injured by suture and penetration with a tenaculum and a hypodermic needle and each of the six puncture wounds produced monitored for up to seven days for the development of ulcers. Altogether 26 lesions were induced in 13 patients, whereas none occurred in the controls (p less than 0.001). Sutures c...

Nicorandil has been shown to precipitate persistent ulcerative stomatitis in a small percentage of patients. To date over 50 cases have been reported, initially in France and, more recently, in the United Kingdom and Portugal, but this is the first report of nicorandil-induced ulceration in Irish medical or dental literature. It has been suggested that a previous history of aphthous ulceration ...