Once a recombinant DNA is inserted into bacteria, these bacteria will make protein based on this recombinant DNA. This protein is known as “Recombinant protein”. The demand of recombinant proteins has increased as more applications in several fields become a commercial reality [1]. For instance, today, more than 75 recombinant proteins are utilized as pharmaceuticals, and more than 360 new medi...

Once a recombinant DNA is inserted into bacteria, these bacteria will make protein based on this recombinant DNA. This protein is known as “Recombinant protein”. The demand of recombinant proteins has increased as more applications in several fields become a commercial reality [1]. For instance, today, more than 75 recombinant proteins are utilized as pharmaceuticals, and more than 360 new medi...

Once a recombinant DNA is inserted into bacteria, these bacteria will make protein based on this recombinant DNA. This protein is known as “Recombinant protein”. The demand of recombinant proteins has increased as more applications in several fields become a commercial reality [1]. For instance, today, more than 75 recombinant proteins are utilized as pharmaceuticals, and more than 360 new medi...

the delivery of therapeutic proteins has gained momentum with development of biotechnology. however, large molecular weight, hydrophilic nature and susceptibility to harsh environment of gastrointestinal tract (git) resulted in low absorption. the main objective of this work was the design of a particulate system for oral delivery of recombinant human growth hormone (rhgh) on the basis of parti...

Rose-Bengal test, complement fixation test and the agglutination are mainly used for diagnosis of animal brucellosis. These tests characterized by low sensitivity specificity, which is one main reasons effectiveness measures aimed at eradicating The use modern highly sensitive serological requires availability antigens specific to Brucella spp. aim study was obtain multiproteins pathogen recomb...

Production and purification of human growth hormone using a simple method was studied in two recombinantEscherichia coli, D7-5 and C27-2 strains. The r-hGH was expressed in the form of inclusion body in a batchfermentation process and purified to 99% purity using a procedure based on acid precipitation of the hostderived proteins and other impurities. The effect of the pH and ...

one of the emerging therapeutic strategies for targeted treatment of most cancers is the use of immunotoxins which are fusion proteins consisted of a targeting and a toxic moieties. we previously showed that the recombinant a254-gmcsf fusion protein selectively kills acute myeloblastic leukemia cells which harbor a large number of granulocyte-macrophage colony stimulating factor (gmcsf) recepto...