Background Ischemic cell death is characterised by cellular oedema. Reperfusion may be expected to increase myocardial oedema via hyperaemia and osmotic changes. Cardiovascular magnetic resonance (CMR) can be used to detect oedema using T2 weighted imaging, but this technique does not allow the study of possible changes in oedema with reperfusion. The purpose of this study was to examine the de...

Pterygium is thought to be hyperaemia of fibrovascular tissue on to the cornea caused by ultraviolet radiation of sunlight. We observed a significantly high incidence of pterygia in welders who were exposed occupationally to excess ultraviolet radiation and found a close relationship between the incidence and the length of employment as a welder (r = 0.975, p less than 0.05). This study attempt...

OBJECTIVE To evaluate the dynamics of skin microvascular blood flow (BF) and tissue oxygenation parameters (OXY) measured simultaneously at the same site using a combined non-invasive BF+OXY+temperature probe. METHODS Skin BF, oxygenated (oxyHb) and deoxygenated (deoxyHb) haemoglobin and mean oxygen saturation (SO2 ) were measured in 50 healthy volunteers at rest and during perturbation of lo...

BACKGROUND/PURPOSE This study has evaluated a multi-parametric system combining laser Doppler flowmetry and photoplethysmography in a single probe for the simultaneous measurement of blood flow at different depths in the tissue. This system will be used to facilitate the understanding of pressure ulcer formation and in the evaluation of pressure ulcer mattresses. METHODS The blood flow in the...

1. Skin microcirculation was investigated in 12 asymptomatic subjects and 76 patients, grouped according to their ankle-to-brachial systolic blood pressure index, in order to evaluate to what extent posturally induced microvascular constriction is dependent on the stage of leg ischaemia at different local skin temperatures. 2. Skin microcirculation was assessed in the supine and sitting positio...

AIM To compare microvascular reactivity assessed in the skin using laser Doppler fluximetry (LDF) in women with gestational diabetes mellitus (GDM) and gestational age-matched control during pregnancy. METHODS 110 pregnant women at ~33 weeks gestation participated in the study. Skin microvascular reactivity was evaluated by LDF, at rest, during the response to brief arterial occlusion (post o...

A fluid extract of the bark was several years ago introduced to the notice of the medical profession, and it is stated by physicians to be a direct sedative, producing narcotic effects, which are refreshing, and not followed, as in the case of opium, by hyperaemia of the brain, nausea and general nervous disturbance. It is said to be also of value in bronchitis, asthma, spasms of the muscles, d...

BACKGROUND Post-occlusive skin reactive hyperaemia (PORH) is a model used to assess microvascular reactivity. This study aims to compare PORH response among pregnant hypercholesterolaemic patients with age and gestational age-matched controls. METHODS This cross sectional study involved 17 hypercholesterolaemic, pregnant women and 20 pregnant controls entering their early third trimester. Las...