In the present study, a novel laccase from ascomycete Gliomastix murorum was produced in agro-industrial wastes and entrapped galactomannan beads for Reactive Blue 2 (Rb-2) decolorization. The maximum production agave bagasse-based medium occurred at 72 h (1798.6 UL−1). Entrapped decolorized ˃80% of 0.5 mM Rb-2 without addition redox mediator. Km substrate 1.42 mM, with Vmax 1.19 µmol min−1 lac...

mycophenolic acid (mpa) is the active metabolite of mycophenolate mofetil. this study designed to investigate the mechanism of cytotoxicity of mpa on the genetically engineered pc12 tet off (pto) neuronal cells with p53 gene. alamar blue (ab) reduction showed concentration-dependent cytotoxicity of mpa on pto cells with ic50 value of 32.32 ± 4.61 mm. the reactive oxygen species (ros) generation...