Endometrial cancer Double uterus Histopathology Abstract We report a rare case of endometrial carcinoma arisen from both horns of an asymmetrical double uterus. Dr. Yoshiharu Tsukahara, Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390 (Japan) Introduction Although the incidence of a malformed uterus is not so rare, there have been few re...

Uterine bacterial community abundances shift throughout the estrous cycle, potentially altering immunological environment of uterus and impacting subsequent fertility. The objective current study was to evaluate impact lipopolysaccharide (LPS), as a model for pathogenic bacteria, uterine endometrium between luteal follicular phase cycle. Bovine tracts were harvested in mid-luteal (n = 7) or pha...

Three experiments were carried out to evaluate the use of ultrasonography in assessing the onset of puberty in gilts. In experiment 1, gilts (n = 17) were scanned 3 times per week beginning at 133 and continuing until 187 days of age. The ultrasonic appearance of the uterus was described, quantified and compared with the reproductive status observed at slaughter. The quantification of the pictu...

Although acotiamide hydrochloride hydrate (acotiamide-HH) has not been reported to have genotoxic findings in any of the genotoxicity studies or treatment-related toxicological findings in reproductive and developmental studies, suspicious uterine tumorigenesis was observed in the results of a long-term rat carcinogenicity study. To clarify the uterine tumorigenesis of acotiamide-HH, we perform...

Calreticulin (CRT), a Ca(2+)-binding storage protein and chaperone in the endoplasmic reticulum, modulates cell adhesiveness and integrin-dependent Ca(2+) signaling. However, the role of CRT during implantation remains poorly understood. In the present study, we characterized the expression of CRT mRNA and the protein in mouse endometria from pregnancy DI to D7. Real-Time PCR and in situ hybrid...

Conventionally, G protein-coupled receptors are thought to increase calcium via inositol 1,4,5-trisphosphate (InsP(3)). More recent evidence shows that an alternative second messenger, nicotinic acid adenine dinucleotide phosphate (NAADP), also has a role to play, causing researchers to question established calcium releasing pathways. With the recent development, by our group, of cell-permeant ...