نتایج جستجو برای: rat heart
تعداد نتایج: 648004 فیلتر نتایج به سال:
Isolated kidneys taken from normotensive Wistar-Kyoto rats were cross-perfused extracorporeally by normotensive strain-matched donor rats. The extracorporeal perfusion circuit was arranged so that the perfusion pressure to the normotensive recipient kidney could be varied from 90 to 200 mm Hg without any change in total flow through this circuit. This setup avoided hemodynamic or mechanical int...
this study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (cpb) and to explore the underlying mechanism. twenty-four male adult sprague dawley (sd) rats were divided into 4 groups. then, the rat cpb model was established. a 14g trocar was inserted into the atrium dextrum. for rats in s1 and s5 groups, sufentanil (1 µg•kg-1...
Objective: It was reported exercise and herbal medicine can possess synergistic effects to control of diabetes complications. The purpose of the present study was investigation of the effects of high-intensity interval training (HIIT) and taking curcumin supplement on activity levels of GPX and MDA of heart tissue in diabetic rats. Materials and Methods: Thirty-two male Wistar rats were random...
Transportation of laboratory rodents unavoidably causes stress. Nevertheless, very little is known about the effects of transportation and how long it takes for the animal to recuperate. In the present study, we investigated physiological and behavioral parameters before and after transportation in both transported and nontransported animals. We took blood samples to analyze plasma corticostero...
Coronary flow (CF) measured ex vivo is largely determined by capillary density that reflects angiogenic vessel formation in the heart in vivo. Here we exploit this relationship and show that CF in the rat is influenced by a locus on rat chromosome 2 that is also associated with cardiac capillary density. Mitochondrial tryptophanyl-tRNA synthetase (Wars2), encoding an L53F protein variant within...
31. Sapirstein LA: Regional blood flow by fractional distribution of indicators. Am J Physiol 193: 161, 1958 32. Neely JR, Rovetto MJ, Whitmer JT, Morgan HE: Effects of ischemia on function and metabolism of the isolated working rat heart. Am J Physiol 225: 651, 1973 33. Rovetto MJ, Whitmer JT, Neely JR: Comparison of the effects of anoxia and whole heart ischemia on carbohydrate utilization in...
Introduction: The effect of regular exercise in decreasing the incidence of heart diseases is well known. The abuse of anabolic androgenic steroids (AAS) has been associated with cardiovascular disorders. Uncoupling proteins (UCPs) transport protons across the inner mitochondrial membrane thereby proton gradient can be diminished by the action of UCPs. This process will result in the uncoupl...
Integrin linked kinase (ILK) is a serine/threonine protein kinase implicated in the phosphatidylinositol 3’kinase (PI3’K) pathway. Integrin linked kinase has been investigated in different organisms such as mammalian systems (human, mice, rat), insects (Drosophila) and nematodes (Cenorhabditis elegans), however to date little data regarding ILK research on amphibians has been reported. In...
Introduction & Objective: The role of free radicals in reperfusion injury has been revealed in the previous studies. Protective effects of endogenic antioxidants include glutathione has been shown in cardiomyocyte. Intracellular L-cysteine availability is one of the major rate limiting factors in glutathione production. This study aimed to investigate the role of L-cysteine in the preservation ...
AIM To investigate the effects of urethane on renal sympathetic nerve activity (RSNA) in Wistar rats. MATERIALSAND METHODS 46 rats were randomly allocated in two groups: group A in which rats were injected with urethane; group B in which barbital sodium was used as a control. The changes of RSNA, blood pressure (BP) and heart rate (HR) of each group were evaluated and analyzed. RESULTS Comp...
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