In a group of 181 persons with a past history of chronic gastric ulcer, a greatly increased incidence of domestic and financial stress has been found, when compared with age-and sex-matched persons with no previous history of gastric ulcer. The consumption of aspirin, alcohol, and cigarettes was also significantly increased. Persons with chronic gastric ulcer were characterized by a personality...

Lysolecithin is formed when pancreatic juice and bile mix in the duodenum. Lysolecithin concentrations have been measured in intermittent samples of night gastric juice from patients with gastric ulcers and duodenal ulcers and in normal controls. In gastric ulcer patients, the mean of the peak concentrations (444 mug/ml) and mean of concentrations in all samples (199 mug/ml) were significantly ...

Basal serum gastrin in 40 patients with benign gastric ulcer was 103 +/- 10.7 pg/ml, a level significantly higher than corresponding estimations in normal subjects and patients with duodenal ulcer. Following stimulation by a protein meal, a mean rise of 124 pg/ml was achieved at 75 minutes and prior atropinization induced a rise of 208 pg/ml at 90 minutes. Insulin hypoglycaemia produced a rise ...

The goal of this study is to investigate the antiulcer effects betalain-rich extract (BRE). Gastric ulcer was induced by administration ethanol gastric gavage route. This showed that supplementation BRE from pulp and peel at 800 mg/kg rats with ethanol-induced gastric-ulcer significantly reduced volume secretion (VGS) 35% ( p <m...

The effect of Methanolic, chloroform and diethel ether extracts of Mimosa pudica was investigated in rats to evaluate the anti-ulcer activity by using three models, i.e. Aspirin, Alcohol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The result...

AIM To investigate the correlation among the presence and degree of gastric metaplasia of duodenal regenerating mucosa, the deformity of bulb and the recurrence of duodenal ulcer. METHODS A total of 99 patients with duodenal ulcer were treated with H(2)-antagonist with or without antimicrobial therapy. All patients received follow-up endoscopic examinations 6 wk after treatment. When the ulce...

background: it is not yet known which types of toll-like receptors (tlrs) are most effective in helicobacter pylori (h. pylori) recognition. it is also not known which gastric zones have the most prominent roles in tlr-mediated bacterial recognition. the aim of this work was to analyze the expression of tlr2 and tlr4 in biopsy specimens from h. pylori-infected patients. methods: thirty-eight pa...

Although colonization with any Helicobacter pylori strain is associated with peptic ulcer, it is uncertain whether the risk is greater with cagA(+) or cagA(-) strains, which differ in their biology. A nested case-control study was done, based on a cohort of 5,443 Japanese-American men examined on the Hawaiian island of Oahu from 1967 to 1970. A total of 150 men with gastric ulcer, 65 with duode...

1. Gastric juice was obtained during continuous maximal stimulation with histamine diphosphate, 0.13 pmol h-' kg-l (0.04 mg h-' kg-l) intravenously, in thirtyfour control subjects, twenty-eight patients with duodenal ulcer, and eighteen with gastric ulcer. After correction for pyloric losses, the average rate of outputs of water, and of H', Na', K+ and C1were determined. 2. The results were ana...