El angiosarcoma hepático (AH), también llamado sarcoma de Kupffer, es una neoplasia maligna poco frecuente, que corresponde a menos del 2% los cánceres hepáticos, con predominio tres veces mayor en hombres. Sin embargo, al tumor mesenquimatoso maligno más común hígado.[1] [2] [3]

Recent data have shown that the PML-RARa fusion gene resulting from translocation t(l5;17) isa highlyreliable molecular marker of acute promyelocytic leukemia (APL). In this study performed on 97 Chinese patients with APL, the retrotranscriptase/polymerase chain reaction (RT/PCR) was used to evaluate the clinical relevance of the long (L) or short (S) PML-RARa fusion mRNA isoforms and to study ...

Perturbation in the transcriptional control of genes driving differentiation is an established paradigm whereby oncogenic fusion proteins promote leukemia. From a retinoic acid (RA)-sensitive acute promyelocytic leukemia (APL) cell line, we derived an RA-resistant clone characterized by a block in transcription initiation, despite maintaining wild-type PML/RARA expression. We uncovered an aberr...

cute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia with unique morphologic, cytogenetic, molecular and clinical features. Besides the classical hypergranular variant, there is also a cytological microgranular variant with significant clinical implications in both children and adults. Moreover, a basophilic form and a hyperbasophilic microgranular variant have been describe...

New data on Chinese Tersilochinae are provided: one species, Tersilochus scutatus sp. n., is described from Liaoning province of China and the Russian Far East, and two species, Barycnemis bellator (Müller) and Tersilochus curvator Horstmann, are new records from China. Thus, this work raises the total number of known Chinese species to 31. Two close species, Diaparsis pulchra Khalaim and D. ra...