AIMS To help clinicians to identify the severity of alcohol use disorders (AUDs) from optimal thresholds found for recommended scales. Especially, taking account of the high prevalence of alcohol dependence among patients admitted to the emergency department (ED) for acute alcohol intoxication (AAI), we propose to define thresholds of severity of dependence based on the AUDIT score. METHODS A...

D This paper presents an extended and-or tree and an extended WAM (Warren Abstract Machine) for efficiently supporting both and-parallel and or-parallel execution of logic programs on shared-memory multiprocessors. Our approach for exploiting both andand or-parallelism is based on the binding-arrays method for or-parallelism and the RAP (Restricted And-Parallelism) method for and-parallelism, t...

Self-animating image of flow through repeated asymmetric patterns (RAPs) is an innovative approach for creating illusory motion using a single image. In this paper, we present a smooth cyclic variable-speed RAP animation model that emulates orthogonal advancing waves from a geometry-based flow representation. It enables dense, accurate visualization of complex real-world flows using animated st...

Antiphospholipid Syndrome (APS) is characterized by vascular thrombosis and/or pregnancy morbidity occurring in patients with persistent antiphospholipid antibodies (aPL). The primary objective of the APS Treatment Trends Task Force, created as part of the 14th International Congress on aPL, was to systematically review the potential future treatment strategies for aPL-positive patients. The ta...

Introduction. Intermittent visceral distress syndrome is described as "at least three scenes of visceral distress, sufficiently severe to hinder their actions over a time longer than 3 months, continuing from the preceding year". Organic factors causing abdominal pain are rare, so most of the children with an intermittent visceral distress are designated to have a functional abdominal pain. Thi...

Conformational changes in ras p21 triggered by the hydrolysis of GTP play an essential role in the signal transduction pathway. The path for the conformational change is determined by molecular dynamics simulation with a holonomic constraint directing the system from the known GTP-bound structure (with the gamma-phosphate removed) to the GDP-bound structure. The simulation is done with a shell ...

This paper analyzed the variations of two air temperature indices, diurnal range (DTR) and annual (ATR), calculated based on observations at Zagreb Grič Observatory over a period 133 years (1887–2019). In intense climate changes strongly manifested by increased temperature, these indices were determined to significantly impact human health environment. effect is especially evident in urban area...

Epithelial cells mostly orient the spindle along the plane of the epithelium (planar orientation) for mitosis to produce two identical daughter cells. The correct orientation of the spindle relies on the interaction between cortical polarity components and astral microtubules. Recent studies in mammalian tissue culture cells suggest that the apically localised atypical protein kinase C (aPKC) i...

Streptomyces ambofaciens RP181110 produces the macrolide polyketide spiramycin. Like many other Streptomyces species, the RP181110 strain is prone to genetic instability involving genomic rearrangements (deletions and/or amplifications) in the large unstable region of the genome. It has previously been demonstrated that the amplification of a particular locus (AUD205) affects spiramycin biosynt...

We describe an implemented two layer architecture for real-time task execution in physical agents. The system integrates the RAP system with a set of dynamically configurable reactive processes called skills. Thus the notion of a primitive action is replaced by the selection of a set of skills that interact directly with each other and with the world to form a reactive agent. Using this approac...