نتایج جستجو برای: randomized clinical trial
تعداد نتایج: 1462313 فیلتر نتایج به سال:
Selpercatinib, a novel, highly selective and potent, inhibitor of RET, demonstrated clinically meaningful antitumor activity with manageable toxicity in heavily pretreated treatment-naive RET fusion-positive non-small-cell lung cancer patients Phase I/II clinical trial. LIBRETTO-431 (NCT04194944) is randomized, global, multicenter, open-label, III trial, evaluating selpercatinib versus carbopla...
Background and Objectives: Randomized clinical trials are the gold standard for evaluating the effectiveness and safety of medical interventions. Some unpredictable challenges may affect the results of these studies. Therefore, the aim of this study was to identify the challenges of clinical trial studies in different stages including design, conduct, analysis, and reporting. Methods: This ...
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Background: Anxiety reduction in patients with myocardial infarction (MI) is essential due to severe complications. The current methods of treatments are primarily medical, while effective and safe treatments which accord with cultural and religious beliefs appear to have higher performance. Aim: survey the effect of Quran on the anxiety of patients with MI admitted to CCU. Methods: The present...
Background and Aim: Randomized controlled clinical trial is the most valid type of epidemiological studies for the treatment of diseases. The aim of the present article is to determine the subject area, type of intervention, and blinding methods used in this type of study design. Materials and Methods: This is a cross-sectional descriptive study in which all the articles based on randomized c...
Background & Aim: Randomized clinical trials (RCTs) are studies which are able to provide the most valid evidence to compare various interventions in health research. Biases can affect the quality of research and ultimately make the results of a study invalid. One of the most important biases is selection bias. The best way to reduce selection bias is the use of random allocation. The aim of th...
This is a report of a cluster randomized clinical trial evaluating the effectiveness of a church-based educational intervention aimed at improving African Americans' (AA) participation in clinical trials. Two hundred and twenty-one AA subjects ages ≥50 years from six predominantly AA churches were randomized to intervention or control condition. The intervention included three educational sessi...
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