There is now ample evidence that brachial artery pulse pressure (PP) is an independent predictor of cardiovascular (CV) outcomes, principally in subjects aged .59. This finding has been observed not only in European but also in American and Asiatic populations. The results of PROCAM, which involves a 10-year follow-up of more than 20 000 subjects, allow new prospective views on this finding. In...

On the lining of alveolar membrane of the lung presence of surfactant, a surface tension lowering agent which is a phospholipid in nature, is well established. A good correlation exists between pulmonary lecithin, the principle constituent of surfactant system and alveolar stability. The production of surface active material in the type II cells is oxygen dependent and is affected by hypoxia. T...

DESTRUCTION of the natural environment of upland game birds and ever-increasing pressure for more birds for hunting have led to attempts by conservationists to utilize artificially propagated birds for restocking. Sportsmen and others concerned with the artificial or controlled production of these birds have learned through costly experience that losses from pathological factors are often treme...

Divergence paralysis is characterized by acquired horizontal homonymous diplopia when viewing distant objects but without limitation of ocular movements (Bielschowsky, I935). Although raised intracranial pressure is a significant aetiological factor in the production of divergence paralysis (Bender and Savitsky, I940; Chamlin and Davidoff, I950, 1951), there has been much diversity of opinion a...

INTRODUCTION The aim of this study was to examine whether circulating levels of the pro-inflammatory glycoprotein tenascin-C (TNC) are elevated in musculoskeletal disorders including rheumatoid arthritis (RA) and to assess in RA whether levels are related to clinical disease status and/or patient response to treatment. METHODS TNC in serum or plasma was quantified by ELISA. Samples from 4 coh...

Two cases of infantile cortical hyperostosis are reported. Both had raised immunoglobulins. Particularly remarkable were the IgA and IgM levels, a finding infrequently reported.

There is no doubt that high blood lead levels are associated with mental subnormality and hyperactivity. Several recent studies in Britain and America have investigated the relation between moderate levels, i.e. between 20 and 40 microgram/100 ml and behavioural and cognitive phenomena. Epidemiological studies have generally failed to point to a clearcut relation between such levels and overact...

The priority that Tessman’s argument gives to phenomenological and neuropsychological explanations of moral requirements entails a fundamental shift in our understanding of these. Two central problems of normative theory come together in Tessman’s account. The first arises when an agent’s sense of requirement clashes with what a systematic theory prescribes. The second arises when neuropsycholo...

Unlike experiments carried out on humans and animals, applications involving microorganisms and their genetic modification do not cause pain and suffering as generally understood. The ethical problems raised by genetically modified microorganisms (GMMs) therefore mainly related to the impact they have on the Earth's biosphere. As microorganisms can be found everywhere, including in the ecologic...