background: radioprotective effect of famotidine was previously shown on radiation induced micronuclei and chromosomal aberrations in human peripheral lymphocytes and mouse bone marrow cells however, its radioprotective property has never been studied in mouse spermatogenesis. it was also shown that vitamin c as an antioxidant also exert its radioprotective effect on many biological systems, bu...

Background: The search for potent radioprotective agents for the amelioration of radiation side effect is an important aim in radiobiology. The present study aimed to evaluate the effects of curcumin and seleno-L-methionine against radiation-induced micronucleus formation in rat bone marrow.Methods: In total, 40 male rats were divided into 8 groups (n=5 each), including control, curcumin or sel...

Radioprotecting ability of the natural polyphenol, gallic acid (3,4,5-trihydroxybenzoic acid, GA), was investigated in Swiss albino mice. Oral administration of GA (100 mg/kg body weight), one hour prior to whole body gamma radiation exposure (2-8 Gy; 6 animals/group), reduced the radiation-induced cellular DNA damage in mouse peripheral blood leukocytes, bone marrow cells, and spleenocytes as ...

In experiments on mice the study of radioprotective and radiotherapeutic efficacy combined use selenium-containing feed additive DAFS-25k iodine-containing preparation Monclavit-1 was carried out. It has been shown that intragastric administration oil solution 3 hours before total, external, single exposure to γ-radiation, subsequent (in 12 hours) an aqueous Monclavit-1, increases survival rate...