the major objective of the present study was to characterize the effects of oxidants generated b xanthine (x) plus xanthine oxidase (xo) on isolated rat ileum motility. the effects of three concentrations of x/xo on the basal tone of the rat ileum preparation were studied for 20 minutes. developed tensions were measured in mg/mg tissues and then expressed as percentage of baseline tension. also...

BACKGROUND Since free radical scavengers of parasite origin like glutathione-S-transferase and superoxide dismutase are being explored as prospective vaccine targets, availability of these molecules within the parasite infecting different hosts as well as different sites of infection is of considerable importance. Using Clinostomum complanatum, as a model helminth parasite, we analysed the effe...

introduction: dye removal from industrial wastewater has been considered as one of the most environmental issues. recently, new methods of treatment such as catalytic ozonation have been used to increase dye removal efficiency. so, the efficiency of catalytic ozonation by copper coated zeolite as a catalyst in the removal of reactive red 198 was investigated. materials & methods: in order to re...

BACKGROUND Active oxygen species can influence vascular tone and platelet activation through a variety of mechanisms. This study assessed the role of the superoxide anion, the hydroxyl radical, and hydrogen peroxide in vasoconstriction and mural thrombosis after coronary artery angioplasty in intact dogs. METHODS AND RESULTS Injury was induced by inflation of a balloon catheter 50 +/- 6% abov...

Glucose-6-phosphate dehydrogenase (G6PD) deficient subjects are vulnerable to oxidative stress. Quercetin, a flavonoids, has been employed as a potent oxygen-free radical scavenger in order to assess the protective effects of quercetin against H2O2-induced oxidative damage in G6PD-deficient and normal human erythrocytes. Erythrocytes of G6PD-deficient (n = 10) and normal (n = 10) subjects were ...

Objective: Ionizing radiation induces deleterious effects in the biological systems by producing free radicals. Grape Seed Extract (GSE) as a free radical scavenger could protect the body against the damages. Materials and Methods: In this study, 12 healthy male volunteers were divided into Groups 1, 2, 3 and 4 and received 100, 300, 600 and 1000...

We introduce a general and relatively straightforward protocol aimed at determining the absolute photoinduced radical generation efficiency via NMR monitoring. This approach relies on use of scavenger probe that combines nitroxide moiety specifically reacts with radicals trifluoromethyl group used as 19F signaling unit. Using an LED source, whose fluence is precisely determined by chemical acti...

Glucose is one of the most important sources of cellular nutrition and glucose deprivation induces various cellular responses. In Schizosaccharomyces pombe, zinc finger protein Rst2 is activated upon glucose deprivation, and regulates gene expression via the STREP (stress response element of Schizosaccharomyces pombe) motif. However, the activation mechanism of Rst2 is not fully understood. We ...

Our phytochemical study focused on the leaves of Citrus deliciosa Algerian origin, in order to evaluate its antioxidant activity and acute toxicity, using scavenger DPPH radicals, ABTS toxicity. The ethanol extract contains 85.62 ± 2.24 μg /mg dried matter 3.02 0.17 μg/mg matter. was confirmed against radical (IC50 = 252.07 0.02 /mL) 398.26 0.01 /mL). No mortality or abnormal behavior observed ...

Iron chlorin e6 (FeCe6) has recently been proposed to be potentially antimutagenic and antioxidative. However, the antioxidant property of FeCe6 has not been elucidated in detail. In this study, we investigated the ability of FeCe6 to scavenge hydroxyl radical and to protect biomolecules and mammalian cells from oxidative stress-mediated damage. In electron spin resonance (ESR) experiments, FeC...