Introduction: During intensity modulated radiation therapy (IMRT) technique, theoretically, presence of flattening filter (FF) across the beamline of clinical linear accelerator (linac) is not essential to obtain uniform lateral profiles due to intensity modulation of photon beams by multileaf collimators (MLCs). The aim of this study was to investigate the dosimetrical propert...

The inhaled corticosteroid fluticasone furoate (FF) and the long-acting β₂ agonist vilanterol (VI) are in development as a combined once-daily therapy for asthma and chronic obstructive pulmonary disease. Our study objectives were to compare the efficacy and safety of once-daily FF/VI with FF alone and twice-daily fluticasone propionate (FP) in patients aged ≥12 years with moderate-to-severe pe...

The local regulation of ovarian aromatase enzyme in polycystic ovary syndrome (PCOS) was studied with aromatase conversion and [11C]vorozole-binding assays to analyze aromatase activity, substrate-enzyme affinity and number of aromatase binding sites in non-cultured human granulosa cells (GC) incubated with different sources and preparations of follicular fluid (FF). Incubation with FF from wom...

A rack of order n is a binary operation B on a set X of cardinality n, such that right multiplication is an automorphism. More precisely, (X,B) is a rack provided that the map x 7→ x B y is a bijection for all y ∈ X, and (x B y) B z = (x B z) B (y B z) for all x, y, z ∈ X. The paper provides upper and lower bounds of the form 2cn 2 on the number of isomorphism classes of racks of order n. Simil...

Caroline is a wine buff and bon vivant. She likes to stop at her local wine store, Transcendental Tastings, on the way home from work. She browses the aisles looking for the latest releases from her favorite vineyards. Occasionally she picks up a few bottles. She stores these in a rack in a cool corner of her cellar. She and her partner eat out frequently but when they are at home they usually ...

NATURE METHODS | VOL.10 NO.4 | APRIL 2013 | 361 We present a genome-wide approach to map DNA double-strand breaks (DSBs) at nucleotide resolution by a method we termed BLESS (direct in situ breaks labeling, enrichment on streptavidin and next-generation sequencing). We validated and tested BLESS using human and mouse cells and different DSBs-inducing agents and sequencing platforms. BLESS was a...

BACKGROUND To examine Chinese soldiers' acute stress responses, we did this study. METHODS The soldiers completed the Acute Stress Response Scale (ASRS) when engaged in major tasks, such as earthquake rescue in Wenchuan, Sichuan, and maintaining social stability in Urumchi, Xinjiang. The ASRS has good reliability and validity. The study enrolled 1,832 male soldiers. RESULTS The results show...

The population of Bangladesh is increasing tremendously and to keep pace with the increasing demand of fish protein, farmers intensified fish production from the water bodies which created environmental pollution. To tackle the situation the raft and rack aquaponics experiment was conducted to reduce the water pollution and have vegetable production from high density poly-culture fish ponds. Th...

Frequency facilitation (FF), comprising a rapid and multiple-fold increase in the magnitude of evoked field potentials, is elicited by low-frequency stimulation (LFS) at mossy fiber-CA3 synapses. Here, we show that in freely behaving rats, FF reliably occurs in response to 1 and 2Hz but not in response to 0.25-, 0.3-, or 0.5-Hz LFS. Strikingly, prolonged (approximately 600 s) FF was tightly cor...