The eye and brain develop coordinately during the period of photoreceptor axon ingrowth in the larval stage. The spatiotemporal pattern of ommatidial differentiation in the eye (posterior earlier than anterior) results in a temporal pattern of photoreceptor axon arrival in the brain. In the eye, new ommatidia initiate differentiation at the anterior (left), while older ommatidia add additional ...

The objective of this experiment was to evaluate self-compatibility of two late blooming almond cultivars and identification and introduction of suitable pollinizers from late flowering genotypes, and evaluation of pollen source effect on fruit characteristics to earn high quality nuts for Iranian almond industry. This experiment was carried out in order to determine the best pollinizer for two...

The purpose of this paper is to highlight some hidden Markovian structure the concave majorant Brownian motion. Several distributional identities are implied by joint law a standard one-dimensional motion B and its almost surely unique K on [0,∞). In particular, distribution 2Kt−Bt that R5(t), where R5 5-dimensional Bessel process with R5(0)=0. 2K−B shares number other properties R5, we conject...

Life history theory links human physical and sexual development to longevity. However, there have been no studies on the association of intellectual development with longevity. This observational study investigates the relationship between the onset of intellectual maturity and lifespan through the life histories of composers and creative writers, whose intellectual development can be gauged th...

Huntington's disease (HD) is a devastating neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin, a protein of unknown function. Mutant huntingtin forms intracellular aggregates and is associated with neuronal death in select brain regions. The most studied mouse model (R6/2) of HD replicates many features of the disease, but has been reported to exhibit on...

This work aimed to evaluate the chemical composition and initial growth of soybean seedlings originated from seeds produced under influence soil flooding in crop reproductive period. The experimental design was totally randomized, organized factorial scheme being two cultivars x three soil-flooding periods, traits were disposed four repetitions. When submitting plants at R5 stage, mass thousand...

Human immunodeficiency virus type 1 (HIV-1) clade C causes >50% of all HIV infections worldwide, and an estimated 90% of all transmissions occur mucosally with R5 strains. A pathogenic R5 simian-human immunodeficiency virus (SHIV) encoding HIV clade C env is highly desirable to evaluate candidate AIDS vaccines in nonhuman primates. To this end, we generated SHIV-1157i, a molecular clone from a ...

The bone morphogenetic protein 6 (BMP6) is a crucial inducer of hepcidin, the peptide hormone that regulates iron availability in our body. Hepcidin expression influenced by hepatic heparan sulfate (HS) and heparin administration, suggesting BMP6 interaction with heparin/HS. BMP2/4 subfamily has been deeply characterized to have N-terminal heparin/HS binding domain (HBD), whose basic residues c...