The mol-ecule of the title compound, C42H32N6O, is built up from one pyrazole ring linked to three phenyl rings and to an approximately planar [maximum deviation = 0.0455 (15) Å] quinoxaline system connected to a phenyl-benzohydrazide group. The pyrazole ring assumes an envelope conformation, the C atom attached to the quinoxalin-3-yl ring system being the flap atom. The dihedral angle between ...

Nitration of isoquinoline and phthalazine has been successfully demonstrated using a novel process which does not require strong acids. In this study, nitration of isoquinoline was repeated and the method applied to 1-nitroisoquinoline and the azaaromatics quinoline, quinazoline, quinoxaline and pyridine. Nitration of only quinoline was observed, with a product yield lower than that reported fo...

1. Folic acid and pteroyl-glutamic acid have been examined for their ability to affect acid production by Strep. lacti8 R during a long period of incubation. 2. Evidence has been obtained pointing to the existence in folic acid of two factors with activity in the early and later phases of growth and acidproduction. 3. Quinoxaline can act as an inhibitor of the growth of Strep. Iacti8 R, and bot...

A small library of 6-aminoquinoxalines has been prepared by nucleophilic substitution of 6-fluoroquinoxaline with amines and nitrogen-containing heterocycles under computer-controlled microwave irradiation. Some compounds were found to be potent inhibitors of JNK Stimulatory Phosphatase-1 (JSP-1) in an in vitro biological assay.

The partially bridged resorcin[4]arene cavitand featuring a cleft-shaped recognition site formed by two anti-quinoxaline bridges and four convergent HO-groups was prepared in three steps and characterised by X-ray crystallography; cavitand was found to be a selective receptor for steroidal substrates in CDCl3, with the best binding observed for steroids with a flat A-ring and two H-bonding site...

In the title mol-ecule, C(16)H(11)N(5), the mean planes of the quinoxaline and indazole fragments form a dihedral angle of 10.62 (5)°. In the crystal, weak inter-molecular N-H⋯N hydrogen bonds link the mol-ecules into zigzag chains extending in the [001] direction. The crystal packing also exhibits π-π inter-actions [centroid-centroid distances of 3.7080 (2) and 3.8220 (5) Å], which form stacks...

Use of single-handed dynamic helical macromolecules as nucleophilic catalysts in asymmetric Steglich-type O-to-C aryloxycarbonyl rearrangement 3-substituted indol-2-yl aryl carbonates is demonstrated. Among several poly(quinoxaline-2,3-diyl) copolymers (PQXap) bearing achiral 4-aminopyridin-3-yl groups at the 5-position quinoxaline rings, PQXmdpp and PQXapy, containing N-methylpyrrolidine-fused...