The 1,4-benzoquinone moiety is a common structural feature in a large number of compounds that have received considerable attention owing to their broad spectrum of biological activities. The cytotoxic and antiproliferative properties of many natural sesquiterpene quinones and hydroquinones from sponges of the order Dictyoceratida, such as avarol, avarone, illimaquinone, nakijiquinone and bolin...

In recent years, there has been considerable interest in the potential of quinones as a promising category electroactive species for use aqueous organic redox flow batteries. These materials offer tunable properties and ability to function both positive negative electrolytes, making them highly versatile suitable range applications. Ongoing research focused on improving stability, solubility, p...

Quinones feature prominently as electron acceptors in nature. Their electron-transfer reactions are often highly exergonic, for which Marcus theory predicts reduced electron-transfer rates because of a free-energy barrier that occurs in the inverted region. However, the electron-transfer kinetics that involve quinones can appear barrierless. Here, we consider the intrinsic properties of the par...

In the course of our screening program fbr new antimicrobial substances from microorganisms, a bacterial strain, SC-1801, was found to produce new antibiotics TI801 A, B, C, and D, Here we report the taxonomy of the producing organism, fermentation and isolation, structure elucidation, and biological activity of the antibiotics. They are new quinone and hydroquinone antibiotics and are active a...

Strain-promoted oxidation-controlled cyclooctyne-1,2-quinone cycloaddition (SPOCQ) between functionalized bicyclo[6.1.0]non-4-yne (BCN) and surface-bound quinones revealed an unprecedented 100 % conjugation efficiency. In addition, monitoring by direct analysis in real time mass spectrometry (DART-MS) revealed the underlying kinetics and activation parameters of this immobilization process in d...

Plastoquinol dibenzyl-32P-phosphate was prepared by reduction of plastoquinone with dibenzyl-32P-phosphonate. Catalytic hydrogenation of the product resulted in the reduction of the polyisoprenoid side chain as well as debenzylation. Substantial reduction was also observed with the use of nuclear magnetic resonance for a number of naturally occurring quinones with conditions recommended for qui...

The cytotoxicity of the clinically important antineoplastic quinones doxorubicin, mitomycin C, and diaziridinylbenzoquinone for the Ehrlich ascites carcinoma was significantly reduced or abolished by the antioxidant enzymes catalase and superoxide dismutase, the hydroxyl radical scavengers dimethyl sulfoxide, diethylurea, and thiourea, and the iron chelators deferoxamine, 2,2-bipyridine, and di...