background: radiation-induced molecular changes on the endothelial surface of brain arteriovenous malformations (avm) may be used as markers for specific vascular targeting agents. in this study, we examined the level of expression of platelet endothelial cell adhesion molecule-1 (pecam-1) on brain endothelial cell surface after radiation treatment, with the aim of targeting the radiation-induc...

staphylococcus aureus causes a wide variety of infections worldwide. methicillin-resistant s. aureus is one of most common causes of nosocomial and community acquired infections. the fluoroquinolones are an important class of antibiotics that used to treat infections caused by s. aureus. today, a significant increase in the rate of ciprofloxacin resistance in methicillin-resistant s. aureus str...

pancreatic carcinoma is currently considered as a rapidly progressive and fatal disease, and is typically diagnosed late in its natural course. it is characterized by a poor diagnosis and lack of response to conventional therapy. recent studies have suggested that disulfiram (dsf), a member of the dithiocarbamate family, may have antitumor activity. this study aimed to evaluate the in vitro eff...

in recent century, sustainability has been the most important feature especially in economic, social and environmental issues. so that it has always been the main concern of regional, national and even international planners as the consequent challenges were the main threat to achieving sustainable development of human society. in this study, all aspects of sustainability including environmenta...

BACKGROUND We describe the development and validation of a new quantitative real time PCR (qrt-PCR) method for the enumeration of the toxic benthic dinoflagellate Ostreopsis cf. ovata in marine environment. The benthic Ostreopsis sp. has a world-wide distribution and is associated during high biomass proliferation with the production of potent palytoxin-like compounds affecting human health and...

BACKGROUND Very little is known regarding the persistence of highly pathogenic avian influenza H5N1 viruses in natural settings during outbreaks in tropical countries, although environmental factors may well play a role in the persistence and in the transmission of H5N1 virus. OBJECTIVE To investigate various environmental compartments surrounding outbreak areas as potential sources for H5N1 ...

The publication of the minimum information for the publication of real-time quantitative PCR experiments (MIQE) guidelines (1 ) has turned out to be a defining event in the maturing of quantitative realtime PCR (qPCR) technology. The response from instrument and reagent manufacturers has been universally positive. There has been extensive publicity in print, online, and at scientific meetings, ...

the plaque forming unit (pfu) and tissue culture infectious dose50 (tcid 50 ) methods are used for evaluation of vaccine heat stability and effect of various stabilizers on thermal stability of vaccines. the aim of present study is using real-time pcrtechniquefor estimation of vaccine degradation rate and thermal stability of measles vaccines. lyophilized measles vaccines containing three vario...