OBJECTIVE Obstructive sleep apnea syndrome (OSAS) has been reported to be a new complication of liver cirrhosis with ascites. This fact prompted a study of episodes of sleep apnea as a function of the severity of cirrhosis. METHODS Forty eight patients with type C liver cirrhosis were divided according to the Child-Pugh score into 3 groups: Group A (16 patients with grade A cirrhosis), Group ...

Background: The role of methadone in QTc prolongation, Torsades de Pointes (TdP) arrhythmia and sudden cardiac death has been debated. Because of widespread use of methadone in methadone maintenance treatment (MMT) centers, we aimed to study dose-related effects of methadone on QTc prolongation. Methods: In a comparative observational study, 90 patients who were under MMT were evaluated. Patien...

BACKGROUND Experimental studies suggest that the interval between peak and end of T wave (Tpe) in transmural ECGs reflects transmural dispersion of repolarization (TDR), which is amplified by beta-adrenergic stimulation in the LQT1 model. In 82 patients with genetically identified long-QT syndrome (LQTS) and 33 control subjects, we examined T-wave morphology and various parameters for repolariz...

OBJECTIVE The effects of sevoflurane general anesthesia and bupivacaine selective spinal anesthesia on QT dispersion (QTd) and corrected QT (QTc) interval were investigated. METHODS AND MATERIALS This prospective, randomized, double-blind study was conducted between July and September 2009 in the Urology and General Surgery operating rooms. Forty ASA I-II patients undergoing noncardiac surger...

Cardiac repolarization is prolonged in diabetes mellitus (DM), however the distribution of repolarization durations in diabetic hearts is unknown. We estimated the ventricular repolarization pattern and its relation to the ECG phenomena in diabetic mice. Potential mapping was performed on the anterior ventricular surface in healthy (n=18) and alloxan-induced diabetic (n=12) mice with the 64-ele...

Objective: To clarify the hemodynamic-stabilizing effect of remifentanil in the context of modified electroconvulsive therapy (mECT), we measured electrocardiographic alterations in the corrected QT interval (QTc) and corrected QT dispersion (QTcD), considered predictive of ventricular arrhythmia, during mECT. Methods: Sixty patients scheduled for mECT were divided randomly into 3 groups. Patie...

BACKGROUND There is still debate about the relationship between changes in ventricular repolarization on the surface electrocardiogram and cirrhosis severity. OBJECTIVE To study the relationship between variables related to ventricular repolarization and the clinical severity of the cirrhotic disease. METHODS We selected 79 individuals with hepatic cirrhosis, classified according to the Chi...

Objective: Increased risk for arrhythmias and the association between arrhythmogenic markers symptom severity in antipsychotic-free patients with schizophrenia are understudied. We evaluated changes P-wave dispersion (PWD), corrected QT interval (QTc), QTc (QTcd), JT (JTc), JTc (JTcd), Tpeak-Tend (Tp-e), Tp-e/QT ratio. Method: Fifty-six who were at least 1 month 56 age- gendermatched healthy co...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background : methadone is a synthetic opioid, used in treatment of chronic pains. the current study was carried out to evaluate the qtc interval in iranian causalities (janbazan) of iran-iraq war receiving maintenance methadone treatment. methods : in 2010, one hundred war causalities in isfahan who chronically take daily dos...

OBJECTIVE Studies have shown that therapy with beta-blockers reduces mortality in patients with heart failure. However, there are no studies describing the effects of propranolol on the QT dispersion in this population. The objective of this study was to assess the electrophysiological profile, mainly QT dispersion, of patients with heart failure regularly using propranolol. METHODS Fifteen p...