BACKGROUND AND OBJECTIVES Deletions at the long arm of chromosome 13, mostly at the q14, and monosomy of chromosome 13 are described to be common in multiple myeloma (MM). 13q- has been associated with an adverse outcome and it has been proposed as one of the most important prognostic factors for MM patients. Deletions of 13q14 are rare in monoclonal gammopathy of undetermined significance (MGU...

BACKGROUND A small number of rhabdomyosarcoma (RMS) cases involve the bone marrow. A leukemic presentation of RMS has been reported in a few case series, although almost all cases of leukemic RMS are not completely mimicking leukemia. We encountered a case with RMS cell infiltration of the bone marrow that resembled floating hematological cells. CASE PRESENTATION We encountered a rare case of...

2 Abstract Pointers 7 2.1 Pointer Provenance . . . . . . . . . . . . . 7 2.1.1 Q1. Must the pointer used for a memory access have the right provenance, i.e. be derived from the pointer to the original allocation (with undefined behaviour otherwise)? (This lets compilers do provenance-based alias analysis) . . 7 2.1.2 Q2. Can equality testing on pointers be affected by pointer provenance informa...

Q1 Should RELIEFF be set as ReliefF as in other sources? See throughout article. Q2 Please supply date of meeting, place of publication, name of publisher and page numbers. Q3 Please supply date and place of symposium, place of publication and name of publisher. Q4 Please clarify publication details. Q5 Please supply place of publication. Q6 Please supply place of publication. Q7 Please supply ...

The last decade has witnessed different price trajectories in the international and Chinese agricultural commodity markets. This paper compares and contrasts these dynamic patterns between markets from the perspective of price bubbles. A newly developed right-tailed unit root testing procedure is applied to detect price bubbles in the CBOT and Chinese agricultural futures market during the peri...

Protein C is a vitamin K–dependent zymogen, discovered in 1976 in bovine plasma (Stenflo, 1976). It is derived from the human PROC gene on chromosome 2 (2q13-q14) which contains 9 exons (Rezaie, 1993). Post-translational modifications include -hydroxylation at Asp71, N-linked glycosylation at residues 97, 248, 313 and 329 and ┛-carboxylation of 9 glutamic acid residues which forms the Gla doma...

Dear Editor, The association of CLL with hematologic malignancies such as AML is relatively rare [1, 2], with mostly associated with prior cytotoxic chemotherapy [3]. Few reports of untreated CLL manifesting with or followed by AML suggested that each tumor probably evolved from simultaneous expansion of two independent clones, not a common clone [1]. Concomitant AML and CLL having a common clo...

a disease that afflicts individuals regardless of age. It may occur in children, adolescents, or young adults who are born with genetic mutations that predispose them to the disease. It also occurs in the elderly where a lifetime of exposure to environmental or age-related stressors facilitates the acquisition of oncogenic mutations. Regardless of the age of onset, cancer is a multifaceted and ...

Prader-Willi syndrome (PWS) is characterised by infantile hypotonia, feeding difficulties, hypogonadism, small hands and feet, mental deficiency, obesity in early childhood, a particular facial appearance, and a paternally derived 15q11-q13 deletion (approximately 4 million bp in size) in about 70% of subjects, maternal disomy 15 (both 15s from the mother) in 25% of subjects, or an imprinting m...

BACKGROUND It has been suggested that efforts to identify genetic risk markers of autism spectrum disorder (ASD) would benefit from the analysis of more narrowly defined ASD phenotypes. Previous research indicates that 'insistence on sameness' (IS) and 'repetitive sensory-motor actions' (RSMA) are two factors within the ASD 'repetitive and stereotyped behavior' domain. The primary aim of this s...