نتایج جستجو برای: q pcr

تعداد نتایج: 295197  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
P G Mermelstein R C Foehring T Tkatch W J Song G Baranauskas D J Surmeier

In brain neurons, P- and Q-type Ca(2+) channels both appear to include a class A alpha1 subunit. In spite of this similarity, these channels differ pharmacologically and biophysically, particularly in inactivation kinetics. The molecular basis for this difference is unclear. In heterologous systems, alternative splicing and ancillary beta subunits have been shown to alter biophysical properties...

Journal: :international journal of fertility and sterility 0
nafise zarezade samane saboori darabi fariba ramezanali elham amirchaghmaghi gholamreza khalili ashraf moini

background: establishment of viable pregnancy requires embryo implantation and placentation. ectopic pregnancy (ep) is a pregnancy complication which occurs when an embryo implants outside of the uterine cavity, most often in a fallopian tube. on the other hand, an important aspect of successful implantation is angiogenesis. vascular endothelial growth factor (vegf) is a potent angiogenic facto...

2017
Anne F. M. Jansen Teske Schoffelen Julien Textoris Jean-Louis Mege Marrigje Nabuurs-Franssen Ruud P. H. Raijmakers Mihai G. Netea Leo A. B. Joosten Chantal P. Bleeker-Rovers Marcel van Deuren

BACKGROUND In the aftermath of the largest Q fever outbreak in the world, diagnosing the potentially lethal complication chronic Q fever remains challenging. PCR, Coxiella burnetii IgG phase I antibodies, CRP and 18F-FDG-PET/CT scan are used for diagnosis and monitoring in clinical practice. We aimed to identify and test biomarkers in order to improve discriminative power of the diagnostic test...

2011
Didier Raoult Matthieu Million Franck Thuny Patrizia Carrieri

To the Editor—The article on the current epidemic of Q fever in Holland, which has involved more than 4000 diagnoses , is very interesting because it makes it possible to make a preliminary point on the detection of chronic infection , the diagnosis of which is particularly difficult [1]. One of the elements of the diagnosis is serology, and there is an old consensus that the detection of immu-...

Journal: :American journal of clinical pathology 2008
Bingjian Lü Yihu Fang Jing Xu Lipei Wang Fangying Xu Enping Xu Qiong Huang Maode Lai

Our purpose was to investigate the role of SOX9, a novel downstream molecule of beta-catenin, in colorectal cancer. Expression of SOX9 and beta-catenin was detected by immunostaining, quantitative real-time reverse transcription-polymerase chain reaction (Q-PCR), and Western blot in colorectal cancer. The correlation between SOX9 or beta-catenin expression and clinicopathologic parameters was a...

2014
Jincheng Pan Yu Chen Chengqiang Mo Daohu Wang Junxing Chen Xiaopeng Mao Shengjie Guo Jintao Zhuang Shaopeng Qiu

BACKGROUND Desmocollin 3 (DSC3), a member of the cadherin gene superfamily, is associated with pathogenesis of some cancers, but its role in prostate cancer (PCa) remains largely unknown. METHODS DSC3 gene expression level in available PCa microarray dataset was examined using the Oncomine database. DSC3 transcript expression in prostate cell line panel and an independent tissue cohort (n = 5...

Journal: :Rheumatology 2011
Wei Wang Bo Zhong Jian Sun Junling Cao Juan Tian Nannan Zhong Wenxiang Zhao Lifang Tian Peng Xu Dawei Guo Xichi Ju Wei Ma Meng Li Weikun Hou Shemin Lu

OBJECTIVE Primary OA and Kashin-Beck disease (KBD) show similar pathological changes in articular cartilage. The objective was to screen differentially expressed genes between OA and normal cartilage, confirm the candidate gene expression among OA, KBD and normal cartilage, and then clarify its role in vitro. METHODS Differentially expressed genes in OA cartilage were screened by suppression ...

2016
Pyde Acharya Nagarjun

Hepatitis C is blood-borne viral disease worldwide. Chronic hepatitis C infection leads to cirrhosis of the liver, liver failure and liver cancer. Antiviral therapy exists and approximately 50% of infected individuals can be cured. The importance of low cost molecular diagnostic assays are especially important for the developing nations as they are already burdened with increasing number of hep...

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