The gastrin cells of the Japanese quail were studied histologically and immunocytochemically. Cells reacting with antiserum to gastrin (gastrin cells) were demonstrated by the peroxidase-labelled antibody method and showed brownish cytoplasm. They also were stained argyrophil by the Grimelius' silver method. Gastrin cells were found in the epithelium of the pyloric region and small intestine an...

1. Rats were made hypertensive by ligating the aorta between the origins of both renal arteries. Sham-operated animals served as controls. Urinary and renal kallikrein activities, as well as plasma and renal renin activities, were measured 8 and 90 days after surgery. 2. Blood pressure was 155 +/- 6 mmHg on day 8 after aortic ligature and 142 +/- 6 mmHg on day 90; in controls pressures were 107...

We previously showed that specific angiotensin II (Ang II) binding sites are present in the canine nodose ganglion and peripheral vagus nerve, and that unilateral removal of the nodose ganglion results in loss of binding in the ipsilateral nucleus tractus solitarii and the dorsal motor nucleus of the vagus. An association of Ang II binding sites with both afferent and efferent vagal fibers is c...

THE gastric mucous membrane is described as being disposed in three regions, known as the cardiac, fundic, and pyloric. These regions, although distinguished from one another by definite microscopic characters, yet merge gradually the one into the other, so as to present no well-defined lines of demarcation. The actual extent of each region varies in different animals. It has not been sufficien...

In order to elucidate the proliferative behavior of the intestinal metaplasia around gastric cancer, the authors used both in vitro tritiated thymidine (3H-thymidine) autoradiography and in vivo bromodeoxyuridine (BrdUrd) immunohistochemistry for labeling the proliferative cells of the normal pyloric glands and metaplastic gastric glands. The results of the methods were comparable: The labeling...

Neuromodulatory inputs play a critical role in governing the expression of rhythmic motor output by the pyloric network in the crustacean stomatogastric ganglion (STG). When these inputs are removed by cutting the primarily afferent stomatogastric nerve (stn) to the STG, pyloric neurons rapidly lose their ability to burst spontaneously, and the network falls silent. By using extracellular motor...

Modulation of synaptic transmission is a major mechanism for the functional reconfiguration of neuronal circuits. Neurotransmitter release and, consequently, synaptic strength are regulated by intracellular Ca(2+) levels in presynaptic terminals. In identified neurons of the lobster pyloric network, we studied localized, voltage-induced Ca(2+) accumulation and its modulation in varicosities on ...

The accumulation of Cd, Pb, Zn, and Cu in the starfish Asterias rubens was studied in a Norwegian fjord characterized by a gradient of metal pollution in the sediments, ranging from very high metal concentrations at its head to much lower levels at its opening. The concentrations of metals in starfish from natural populations along the gradient (long-term accumulation) and in starfish that were...

Kloppenburg P, Zipfel WR, Webb WW, Harris-Warrick RM. Heterogeneous effects of dopamine on highly localized, voltageinduced Ca accumulation in identified motoneurons. J Neurophysiol 98: 2910–2917, 2007. First published August 29, 2007; doi:10.1152/jn.00660.2007. Modulation of synaptic transmission is a major mechanism for the functional reconfiguration of neuronal circuits. Neurotransmitter rel...

The distinctive motor activity of duodenal bulb is incompletely understood. Thus, in six conscious sheep the myoelectric activity of pyloric antrum, duodenal bulb and distal duodenum were continuously recorded in order to assess the myoelectric patterns of duodenal bulb and the relationships to adjacent regions before and after feeding or cholinergic drug administration. It was found that in du...