Fluorescence measurements are easily made with the aid of a cryogenic fiber optic probe. Emission wavelength time matrixes, excitation emission matrixes, and time-resolved excitation emission matrixes are rapidly collected with a pulsed tunable dye laser, a spectrograph, and an intensified charged-coupled device. Compound identification is based on spectral and lifetime information. The potenti...

We present the first observation, to our knowledge, of lasing from a levitated, dye droplet. The levitated droplets are created by computer controlled pico-liter dispensing into one of the nodes of a standing ultrasonic wave (100 kHz), where the droplet is trapped. The free hanging droplet forms a high quality optical resonator. Our 750 nL lasing droplets consist of Rhodamine 6G dissolved in et...

No particular regimen is considered standard therapy for widespread metastatic melanoma, although surgery is the primary choice for regional nodal metastases. Systemic interleukin-2 (IL-2) is an effective immunotherapy for melanoma, but standard doses are associated with severe toxicity. We report a patient who was treated with intralesional low-dose IL-2 and V-beam pulsed dye laser for the tre...

Multiple light sources can be used for photodynamic therapy (PDT) with good results, but there are few comparative studies. This study compares the efficacy of treatment of basal cell carcinoma with PDT and two light sources, the non-coherent red light and pulsed dye laser 595 nm. In this small pilot study red light is more effective, but many more studies are needed to draw definitive conclusi...

Warts are benign epithelial neoplasms of the skin and mucosa resulting from human Papilloma virus (HPV) infection. They are a common dermatologic complaint, with an estimated incidence of 10% in children and young adults [1]. The treatment is challenging and there is no single therapy established as completely curative [2]. In this report we presented a case of successfully removed resistant pl...

A microstructured polymer optical fiber doped with Rhodamine 6G dye was fabricated and demonstrated as an optical amplifier and a fiber laser. As an amplifier, the fiber achieved a gain in excess of 30 dB. As a pulsed fiber laser, the fiber exhibited a threshold of 20 microJ, a slope efficiency of 18%, and a lifetime as high as 130,000 shots at 10 Hz. The maximum output energy was 16 microJ. Th...

Clinicians always find it difficult to treat hypertrophic scars and keloids. Various treatment modalities are available. Intralesional corticosteroids, topical applications, cryotherapy, surgery, laser therapy, and silicone sheeting are the widely used options. Radiation therapy can also help in cases of recalcitrant keloids. Most recently, pulsed-dye laser has been successfully used to treat k...

Inflammatory linear verrucous epidermal nevus (IL VEN) is a benign hyperplasia of the epidermis of unknown cause that most commonly occurs on the lower extremities.l ? The lesion usually appears in early childhood and is persistent and pruritic. Treatments for ILVEN have been associated with high rates ofrecurrence and/or scarring. This is the first report of successful treatment of ILVEN with ...

BACKGROUND Various lasers, particularly the flashlamp-pulsed dye laser, have been proven to be effective in the treatment of facial vascular lesions. Nevertheless, the post-treatment side effects, such as pronounced purpura and changes in pigmentation, have been a matter of concern to patients. OBJECTIVE To test the efficacy of an alternative treatment option that uses intense pulsed light to...

Background: Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder with cutaneous manifestations including poor wound healing and atrophic scar formation. There evidence supporting the use of topical vitamin C laser for revisions, but limited reports using in revisions patients hEDS. Objective: To present case where applied post-laser treatment resulted improved aesthetic out...