Gravity-driven flow of concentrated suspensions (solid volume fraction ϕ>0.50) of non-brownian spherical particles through a channel contraction at low Reynolds number is studied experimentally. The abrupt change in the flow area at the contraction forms distinct shear-rate regions having different fluid pressures, which are related to the concept of particle pressure. A model involving particl...

Background: The interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries.Objective: To understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from CT...

AIMS Aberrant retinal blood flow is a hallmark of various retinopathies and may be a causative factor in the pathology associated with these conditions. We examined the effects of pulsatile flow on bovine retinal endothelial cell (BREC) and bovine retinal pericyte (BRP) apoptosis and proliferation. METHODS AND RESULTS Co-cultured BRECs and BRPs were exposed to low (0.3 mL/min) or high (25 mL/...

A global nonlinear stability analysis is performed for a couple-stress fluid layer heated from below saturating a porous medium with temperature-pressure dependent viscosity for different conducting boundary systems. Here, the global nonlinear stability threshold for convection is exactly the same as the linear instability boundary. This optimal result is important because it shows that lineari...

The paper presents results of the modelling heat transfer at film boiling a liquid in porous medium on vertical heated wall. Such processes are observed cooling high-temperature surfaces pipes, microstructural radiators etc. Heating conditions wall were constant temperature or flux.
 An analytical solution was obtained for problem fluid flow and using model Darcy-Brinkman. It shown that le...

Abstract: Pulsatile flow in a 3D model of arterial double stenoses is investigated using a large eddy simulation (LES) technique. The computational domain that has been chosen is a simple channel with a biological-type stenosis formed eccentrically on the top wall. The pulsation was generated at the inlet using the first four harmonics of the Fourier series of the pressure pulse. The flow Reyno...

The deformation of fluid elements governs many processes in porous media, including the transport, dispersion and mixing solutes, chemical reactions colloidal particles. Recently, it has been shown that even strongly heterogeneous steady three-dimensional (3-D) Darcy flow with isotropic hydraulic conductivity admits only constrained kinematics. This is due to its inherently helicity-free nature...

Bone cells are subject to interstitial fluid flow (IFF) driven by venous pressure and mechanical loading. Rapid dynamic changes in mechanical loading cause transient gradients in IFF. The effects of pulsatile flow (temporal gradients in fluid shear) on rat UMR106 cells and rat primary osteoblastic cells were studied. Pulsatile flow induced a 95% increase in S-phase UMR106 cells compared with st...

Continuous-flow left ventricular assist devices (LVAD) have become standard therapy option for patients with advanced heart failure. They offer several advantages over previously used pulsatile-flow LVADs, including improved durability, less surgical trauma, higher energy efficiency, and lower thrombogenicity. These benefits translate into better survival, lower frequency of adverse events, imp...