IMPORTANCE Persistent localized pruritus is a rare manifestation of central nervous system tumors. Delayed diagnosis can lead to devastating complications. OBSERVATIONS We report an otherwise healthy 19-month-old girl who presented with signs of localized intractable pruritus of 6 months' duration on the left side of the neck, shoulder, and arm, resistant to systemic antihistamines and topica...

Pruritus with unknown origin is a common complaint and secondary causes should be investigated. We report a 22-year-old man with intractable localized pruritus and painful burning, stinging sensations in the bilateral arms, shoulders, neck and upper back for 3 weeks. A dermatologist was consulted in the emergency department. On physical examination, there were multiple excoriated erythematous m...

39 bullous pemphigoid (BP) patients were studied to assess the clinical significance of anti-BP180 and anti-BP230 circulating autoantibodies of BP and correlate their titers with the clinical scores of the BP Disease Area Index (BPDAI) and the Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) as well as with the intensity of pruritus measured by the BPDAI pruritus component. All paramete...

OBJECTIVE Gabapentin has an antipruritus effect, which its efficacy in reducing pruritus induced by intrathecal morphine has not been well documented. The purpose of the present study was to know if a single smaller dose of gabapentin could decrease the intrathecal morphine-induced pruritus. MATERIAL AND METHOD One hundred sixty eight patients from the 180 recruited patients fulfilled the tri...

The somewhat uncertain aetiology of pruritus vulvae, and, on that account, the many unsatisfactory methods of treatment employed seemed ample reason for an investigation of this condition. Treatment wasrby Amido-benzoic acid (" A.B.A. ") injections, this method being used, firstly, because of its success in pruritus ani; secondly, because no detailed report of its action in pruritus vulvae has ...

Chronic renal disorders have a progressive course in most cases, and finally result in end-stage renal disease (ESRD). Hemodialysis (HD) is one of the mainstays in the treatment of these patients. Disturbance in calcium (Ca) and phosphorus (P) metabolism and alteration of serum levels of parathormone (PTH) are observed in these patients. One of the most common cutaneous manifestations in patien...

BACKGROUND Pruritus is a common symptom among patients on haemodialysis (HD). We studied 68 HD patients to assess the role of iron deficiency, anaemia, inflammation and other common serum and dialysis parameters in pruritus. METHODS The patients were questioned about the occurrence of pruritus at home, quantified according to frequency ('never', 'occasionally' and 'every day') and intensity (...

Bullous pemphigoid disease activity index (BPDAI) is the standard indicator of in bullous (BP). However, examining patients’ whole body burdensome to both patient and health care workers subjected inter-examiner bias, hence need investigate other surrogate markers for BPDAI. The purpose study quantify correlate candidate BP namely visual analogue scale pruritus (VAS-pruritus), thymus activation...