Primary intestinal lymphangiectasia (PIL) is a rare disease of intestinal lymphatics presenting with hypoproteinemia, bilateral lower limb edema, ascites, and protein losing enteropathy. We report a series of 4 children from Chennai, India presenting with anasarca, recurrent diarrhea, hypoproteinemia and confirmatory features of PIL on endoscopy and histopathology.

Despite advances in Fontan surgery, obstruction in extracardiac ducts may occur and cause clinical deterioration. We report two cases of stent implantation for correction of stenosis in the Fontan surgery. Ascites was a common clinical sign; a patient was protein losing enteropathy. All procedures were angiographically and clinically successful.

A 14 year old common variable immunodeficiency patient developed severe protein-losing enteropathy. A chronic enteral infection with human parechovirus type 1 and norovirus was diagnosed. Treatment strategies aimed at virus eradication and providing supportive care were ineffective. The antipicornavirus agent pleconaril did not have any effect on viral replication. Symptoms improved on immunosu...

Correspondence Protein-losing enteropathy caused by systemic lupus erythematosus SIR,-We have read with great interest the recent paper by Wood et al in the September 1984 issue of Gut' referring to a case of protein losing entero-pathy (PLE) complicating the clinical course of a patient with systemic lupus erythematosus (SLE). In our opinion, the work contains some errors and omissions which q...

optic discs were both normal. Foveal schisis and internal limiting membrane changes were observed in each eye (Figure 1). No vitreous detachment was present. Peripherally, there were a localized chorioretinal scar in the right eye and a relatively flat retinoschisis cavity in the left. Electroretinography demonstrated decreased b-wave amplitude, which was consistent with the diagnosis. After ad...

A 73 year old female presented with progressive hypoproteinaemic oedema which was resistant to treatment. The cause was not established until post-mortem, when it was found that she had angiotropic large cell lymphoma involving the vessels of the large intestine with mucosal ulceration. To our knowledge, this is the first report of angiotropic large cell lymphoma, which usually presents with ne...

Case report A 57-year-old male presented with a 10-day history of oedema rising to the level of the xiphisternum. Examination also revealed coarse crepitations over the left upper lung field and finger clubbing. Ten years earlier he had been treated with standard chemotherapy for pulmonary tuberculosis and subsequently developed severe bronchiectasis with persistently purulent sputum. Investiga...

Collagenous mucosal inflammatory disease is a rare gastrointestinal disorder that involves the columnar lining of gastric and intestinal mucosa and is characterized by a distinct subepithelial collagen deposition. Recent clinical and pathological evidence have indicated that collagenous mucosal inflammatory disease can be extensive disease that may concomitantly involve several gastrointestinal...

Protein losing enteropathy (PLE) refers to excessive intestinal protein loss, resulting in hypoalbuminemia. Underlying pathologies include conditions leading to either reduced intestinal barrier or lymphatic congestion. We describe the case of a patient with long-lasting diffuse abdominal problems and PLE. Repetitive endoscopies were normal with only minimal lymphangiectasia in biopsies. Furthe...

Aunque se han descrito diferentes alteraciones del perfil nutricional en los pacientes en programas de diálisis peritoneal1, ni en las guías de práctica clínica2,3, ni en las principales revisiones sistemáticas4 encontramos referencias a los síndromes de malabsorción intestinal, o en general a ningún tipo de enteropatía como factor etiológico de la malnutrición de estos enfermos. Presentamos el...