This study was performed in order to evaluate the effects of irrigation and application of Zn fertilizer on  seed storage proteins  in chickpea, Azad cultivar. Experiment was performed in an factorial using randomized complete block design with three replications. In this experiment, two factor consist of irrigation in three levels (I1= non irrigation and I2= irrigation in...

Salt reabsorption by the loop of Henle controls NaCl handling and blood pressure regulation. Increased oxidative stress stimulates NaCl transport in one specific segment of the loop of Henle called the thick ascending limb (TAL). The isoprostane 8-iso-prostaglandin-F2α (8-iso-PGF2α) is one of the most abundant nonenzymatic lipid oxidation products and has been implicated in the development of h...

This study was aimed to determine whether beta-adrenergic receptor (beta-AR) stimulated by isoproterenol (ISO) activates signal transducers and activators of transcription (STAT) in mouse heart and, if so, to examine the underlying mechanism. We found that treatment of adult male mice by ISO (15 mg/kg body weight, intraperitoneal) caused a delayed STAT3 activation (at 60-120 min), which was ful...

CONTEXT Obesity, in particular abdominal adiposity, is associated with increased cardiovascular morbidity and mortality through mechanisms possibly linking the metabolic disorder to platelet and vascular abnormalities. OBJECTIVE To investigate the clinical and biochemical determinants of lipid peroxidation and platelet activation in obese women. DESIGN, SETTING, AND PARTICIPANTS Cross-secti...

The effect of ionic strength on the proteolysis by trypsin of the major membrane-penetrating protein (polypeptide 3) in the erythrocyte membrane was studied. Both the intracellular and extracellular regions of the protein are susceptible to trypsin proteolysis under hypo-osmotic conditions, whereas under iso-osmotic conditions the extracellular region of the protein is resistant to trypsin, and...

Heart failure (HF) is characterized by cardiac dysfunction along with autonomic unbalance that is associated with increased renin-angiotensin system (RAS) activity and elevated levels of proinflammatory cytokines (PICs). Renal denervation (RD) has been shown to improve cardiac function in HF, but the protective mechanisms remain unclear. The present study tested the hypothesis that RD ameliorat...

This study was performed in order to evaluate the effects of irrigation and application of Zn fertilizer on  seed storage proteins  in chickpea, Azad cultivar. Experiment was performed in an factorial using randomized complete block design with three replications. In this experiment, two factor consist of irrigation in three levels (I1= non irrigation and I2= irrigation in...

Leishmania are parasitic protozoa with two major stages in their life cycle: flagellated promastigotes that live in the gut of the insect vector and nonflagellated amastigotes that live inside the lysosomes of the vertebrate host macrophages. The Pro-1 glucose transporter of L. enriettii exists as two isoforms, iso-1 and iso-2, which are both expressed primarily in the promastigote stage of the...

The present study evaluated cardioprotective effect of hydro-alcoholic extract of Nepeta hindostana (NH), commonly know as badranjbuyeh in Unani medicine, in the experimental model of isoproterenol (ISO) induced- myocardial infarction. Wistar albino rats were divided in to four groups: sham control, ISO control, NH treatment group and ISO with NH treatment groups. NH was administered at doses o...