A major difference between the prostate and other accessory reproductive glands is the susceptibility of the prostate to hyperplasia in again men. Indeed, benign hyperplasia of the prostate (BPH) affects most males over 60 years of age and causes enlargement of the inner gland. When the urethra becomes constricted, treatment is required to relieve the kidney and circulation system of the damagi...

In this study, a multiparametric magnetic resonance image (MRI) based technique of detecting prostate cancer is developed. A machine learning algorithm, based on random forest is used to classify the normal and cancer regions. Three features extracted from dynamic contrast enhanced MRI and two features extracted from diffusion tensor MRI is used to train the classifier. The classifier is traine...

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Prostate biopsy and needle-directed prostate therapies are currently performed free-handed or with needle external templates under ultrasound guidance. Direct image-guided intervention robots are modern instruments that have the potential to substantially enhance these procedures. These may increase the accuracy and repeatability with which needles are placed in the gland. The authors' group ha...

Prostate biopsy is the only examination that enables urologists to diagnose prostate cancer. It consists in taking off samples of the gland using a biopsy needle that slides in a needle-guide rigidly attached to a transrectal ultrasound probe. In clinical routine twelve systematic biopsies are distributed in the prostate volume and additional targeted samples can be taken in a given zone of int...

Both benign prostatic hyperplasia (BPH) and prostate cancer are age-related diseases in males that develop late in life. The human prostate gland contains several different zones. BPH typically arises within the transitional zone (Tz), whereas prostate cancer predominantly occurs in the peripheral zone (Pz) (Zhao et al., 2009). The reason why both these diseases arise in different zones is uncl...

Currently there are few parameters that are used to compare the efficiency of different form of cancerous prostate surgical removal. An accurate assessment of the percentage and depth of extra-capsular soft tissue removed with the prostate by the various surgical techniques can help surgeons determining the appropriateness of surgical approaches. In order to facilitate the reconstruction phase ...

In prostate cancer, an interesting and intriguing option to overcome the risks of whole-gland treatment is focal therapy, with the aim of eradicating known cancer foci and reducing collateral damages to the structures essential for maintaining normal urinary and sexual function. Ablation of all known lesions would favorably alter the natural history of the cancer without impacting health-relate...