In continuing studies of drugs against Mycobacterium leprae in mice we have tested the following compounds: lincomycin, clinimycin (7( S ) -chloro-7 -deoxylincomycin, clindamycin) , U-24729A (4' -pentylN -demethyl-7 -chlorolincomycin), amicetin, phosphonomycin, ABT-29666 (1-{3-[ 4-(pchlorophenyl-azo )-5, 6, 7, 8-tetrahydro-1naphthylamino] propyl} piperidine), ABT38396 (1{3-[ 4-( 6-methoxy-3-pyr...

Shorea leprosula (damar daging) adalah salah satu tanaman yang dapat digunakan sebagai bahan baku pembuatan plastik biodegradable. Damar daging mengandung senyawa antimikroba sehingga biodegradable dihasilkan juga memiliki sifat antimikroba. Untuk meningkatkan aktivitas dalam dengan penambahan resin, bisa dilakukan kimia lain bersifat Penelitian ini bertujuan untuk mengetahui pengaruh matriks r...

The ability of 19 structural analogs of propyl gallate to inhibit purified soybean seed (Glycine max [L.] Merr. var. Ransom) lipoxygenase-2 (EC 1.13.11.12) was determined. The results indicate that the o-dihydroxy and not the ester function of propyl gallate is essential for inhibition of lipoxygenase. Catechol thus represents the minimum inhibitory structure. Among those compounds possessing a...

Strain improvement and medium optimization to increase the productivity of spiramycin were carried out. Of oil tolerant mutant strains screened, one mutant, Streptomyces ambofaciens XC 2-37, produced 9% more spiramycin than the parent strain S. ambofaciens XC 1-29. The effects of soybean oil and propyl alcohol on spiramycin production with S. ambofaciens XC 2-37 were studied. The potency of S. ...

Precursors involved in the formation of pink and green-blue pigments generated during onion and garlic processing, respectively, have been studied. It has been confirmed that the formations of both pigments are of very similar natures, with (E)-S-(1-propenyl)cysteine sulfoxide (isoalliin) serving as the primary precursor. Upon disruption of the tissue, isoalliin and other S-alk(en)ylcysteine su...

In the title compound, C(17)H(19)NO(4)S, the terminal ethyl group is disordered over two sets of sites, with refined site occupancies of 0.536 (7) and 0.464 (7). The dihedral angle between the two aromatic rings is 81.92 (12)°. The mol-ecular conformation is stabilized by intra-molecular N-H⋯O and C-H⋯O hydrogen bonds, which generate S(6) motifs. In the crystal, mol-ecules are linked by C-H⋯O h...

The etherification of glycerol with propylene over acidic heterogeneous catalysts, Amberlyst-15, S100, and S200 resins, produced mono-propyl glycerol ethers (MPGEs), 1,3-di- and 1,2-di-propyl glycerol ethers (DPGEs), and tri-propyl glycerol ether (TPGE). The propylation of glycerol over Amberlyst-15 yielded only TPGE. The glycerol etherification with 1-butene over Amberlyst-15 and S200 resins p...

In the title compound, C(8)H(9)N(3)S(2), the n-propyl chain is disordered over two orientations (site-occupancy ratio = 0.522:0.478) and is roughly perpendicular to the fused thia-zolotriazine system. The angle between the fused ring and the propyl chain is 83.6 (1)° [ 82.2 (1)° for the disordered chain]. The structure is stabilized by C-H⋯N hydrogen bonds.

Ionosilica ionogels have been lately introduced as emerging all-ionic designer materials. They consist of an ionic liquid (IL) guest trapped within a solid ionosilica support host. In this work, we investigate the influence (i) nature and (ii) ionosilica/IL ratio on mobility confined IL. We report elaboration various via nonhydrolytic sol–gel process, using namely tris(3-(trimethoxysilyl)propyl...