PURPOSE To clarify the clinical validity and feasibility of the diagnostic scheme for seizures and epilepsy proposed by the International League Against Epilepsy (ILAE) in 2001 (the 2001 Scheme) and the report of the ILAE classification core group in 2006 (the 2006 Report). METHODS One hundred consecutive patients with epilepsy who visited the Neurology Clinic (Group 1) and 100 patients with ...

Piracetam, a derivative of gamma-aminobutyric acid (GABA), has been used extensively for treatment of myoclonus in a variety of conditions, but not in patients with idiopathic generalized epilepsy (IGE). We have treated a patient with juvenile myoclonic epilepsy who had frequent and inconvenient morning myoclonus with 3,200 mg of piracetam daily. She had had only two generalized tonic-clonic se...

The incidence of atypical handedness (left-handedness and ambidexterity) in patients with epilepsy, particularly its association with major clinical factors, is not well established. We evaluated a full range of clinical variables in 478 patients with epilepsy from the United States and Korea. With the Edinburgh Handedness Inventory, handedness was established as both a categorical variable (ri...

Case presentation: Three-years-old male attended with a generalized tonic-clonic seizure. No history of traumatic brain injury, fever or associated flu-like symptoms. Days before, aggressive behavior, slurred speech, visual hallucination. Only one previous seizure, month ago, without status epilepticus. Electroencephalogram (EEG): brush pattern extreme delta, cerebrospinal fluid (CSF) IgG+ for ...

Aim: Stevens Johnson Syndrome and Toxic Epidermal Necrolysis (SJS/TEN) is a life-threatening mucocutaneous skin reaction that usually develops against drugs, although there are various factors in its etiology. In this case report, SJS due to antiepileptic drug use will be briefly reviewed. Case:20-year-old female patient was seen the emergency department with generalized tonic-clonic seizure. W...

Hemodialysis-associated seizure is a complication of hemodialysis. This report describes the occurrence of seizures in patients with end stage renal disease on dialysis therapy at the Nephrology Institute of Mogi das Cruzes, São Paulo State, Brazil. A retrospective medical history of 189 patients was reviewed to investigate the occurrence of convulsive seizures during dialytic program. Seven pa...

This study examined both the acute and long-lasting changes in seizure susceptibility that occur in response to the repeated induction of generalized seizure activity. Daily flurothyl-induced generalized clonic seizures resulted in a progressive decrease in both the generalized seizure threshold and the latency to the first myoclonic jerk. The threshold reduction was significant as early as the...

OBJECTIVE New-onset acute symptomatic seizures can be the presenting feature of acute neurological diseases. The etiological spectrum of new-onset acute symptomatic seizures and outcome may be different in developing countries when compared to developed countries. AIM To study the clinical profile of new-onset acute symptomatic seizures as the first presenting event in patients with acute neu...

UNLABELLED Idiopathic generalised epilepsy (IGE) is subdivided into syndromes based on clinical and EEG features. PURPOSE The aim of this study was to characterise all cases of IGE with supportive EEG abnormalities in terms of gender differences, seizure types reported, IGE syndromes, family history of epilepsy and EEG findings. We also calculated the limited duration prevalence of IGE in our...

It has been described that febrile seizures during infancy increase risk of subsequent non-febrile seizures during the adulthood. However, latency period between febrile seizure and the onset of the first spontaneous seizure has not been evaluated. The present study was designed to investigate the susceptibility to subsequent seizures in immature rats that had experienced early-life hyperthermi...