Failure of the ductus arteriosus to close within 48-96 hours of postnatal age results in a left to right shunt across the ductus and overloading of the pulmonary circulation. This is more likely to happen in premature neonates with respiratory distress syndrome. Deterioration in the respiratory status on day 3-4 in a ventilated neonate and unexplained metabolic acidosis may be the earliest indi...

Introduction Hereditary hemorrhagic telangiectasia (HHT, M. Osler) is an autosomal-dominant hereditary disease that can lead to the development of arteriovenous malformation and skin mucous membranes. The leading symptom epistaxis, severity which vary greatly from patient patient. Therapy only symptomatically oriented. In addition surgical medicinal therapy approaches, adequate care nasal mucos...

The aim of the study was to find out the neonatal outcome of infants born with history of preterm premature rupture of membrane (PPROM) and to compare with infants born without history of PPROM. It was a retrospective study that included 187 preterm newborn with history of PPROM admitted in neonatal intensive care unit of the third affiliated hospital of Zhengzhou University from January 2008 t...

We conducted this study to investigate the efficacy of the silicon gel application on the nares in prevention of nasal injury in preterm infants ventilated with nasal continuous positive airway pressure (NCPAP). Patients (n=179) were randomized into two groups: Group 1 (n=87) had no silicon gel applied to nares, and in Group 2 (n=92), the silicon gel sheeting was used on the surface of nares du...

Neonatal jaundice occurs in nearly 70% of term and 80% of preterm babies. Management of jaundiced neonates often requires measurement of total serum bilirubin (TSB). Total serum bilirubin (TSB) is commonly determined by spectro-photometric methods by analyzing plasma or serum sample. Such techniques require drawing of blood causing pain and trauma to the neonate. In addition, there is a wide ra...