Type 2 diabetes mellitus profoundly changes small artery remodeling in response to hypertension. Abnormal increases of both wall thickness and lumen diameter are associated with an increased mortality. Changes to small artery structure in response to blood pressure (BP) in patients with type 1 diabetes mellitus have never been examined. In 1997, 17 patients with type 1 diabetes mellitus and 9 c...

BACKGROUND Type 2 diabetes is strongly linked to an increased incidence of cardiovascular outcomes. Carotid artery intima-media thickness and ankle-arm index are non-invasive complementary measures as subclinical markers of atherosclerosis. OBJECTIVE To evaluate the association of carotid intima-media thickness, ankle-arm index, and inflammation profile in Mexican patients with early- and lat...

OBJECTIVE Carotid intima-media thickness (cIMT) has been known as a criterion of generalized atherosclerosis and a marker of cardiovascular disease progression in many studies which can be measured by ultrasound using high-resolution device. METHODS This is a case-control study. A total of 40 children (16 males and 24 females) with type1 diabetes mellitus and control group consisting of equal...

Background Increased left ventricular (LV) mass is a strong predictor of cardiovascular events and mortality and is common among patients with type 2 diabetes. Carotid intima-media thickness (CIMT) is commonly used to monitor progression of coexisting atherosclerosis. However, the relationship between the progression of LV mass and vascular changes in the carotid and coronary arteries remains p...

Diabetes mellitus (DM) is recognised as a major health problem. Ninety-nine percent of diabetics suffer from type 2 DM and 10% from type 1 and other types of DM. The number of diabetic patients worldwide is expected to reach 380 millions over the next 15 years. The duration of diabetes is an important factor in the pathogenesis of complications, but other factors frequently coexisting with type...

BACKGROUND Early subclinical atherosclerosis has been mainly researched in carotid arteries. The potential value of femoral arteries for improving the predictive capacity of traditional risk factors is an understudied area. OBJECTIVES This study sought to evaluate the association of subclinical carotid and femoral plaques with risk factors and coronary artery calcium score (CACS) in middle-ag...

It is known that blood flow through the carotid artery is decreased during pregnancy, which may be due to a pregnancy-associated increase in the sensitivity of this artery to vasoconstrictors. Recent studies have shown that alteration of blood flow or pressure could remodel some arteries over a short time frame. However, the possibility of remodelling of the carotid artery during pregnancy has ...

BACKGROUND Diabetes mellitus is a common medical disorder in pregnancy. It contributes particularly to perinatal morbidity/mortality, and maternal morbidity. This review aims at improving maternal and neonatal health care especially in Sub-Saharan Africa by improving the knowledge of health practitioners on current evidences in the classification and management of diabetes mellitus in pregnancy...

A 65-year-old man with a history of smoking, hypertension, and diabetes mellitus presented because of sudden-onset left hemiparesis. On admission, neurological examination disclosed a mild left-sided weakness, a normal consciousness level, and a right carotid bruit. The blood pressure, ECG, echocardiogram, and laboratory studies were all unremarkable. He was taking daily aspirin, enalapril, and...