dopaminergic signaling is one of the regulatory pathways being investigated for its implication in glucose metabolism. the aim of this study was to determine the effect of cabergoline on biochemical and anthropometric parameters in prediabetes stage (impaired fasting glucose and impaired glucose tolerance). in this double blind, placebo-controlled, pilot study, 27 prediabetic adults were random...

The regulatory action of insulin on the blood glucose homeostasis is mediated by the Insulin signalling pathway. To quantify this regulation, we have integrated the models of Insulin secretion, insulin signalling, mTOR signalling and blood glucose uptake by various tissues. We have analyzed the effect of perturbations in the integrated insulin-mTOR signalling pathway on blood glucose levels. Th...