OBJECTIVES The aim of this study was to investigate the influence of age at disease onset in the outcome of paediatric SLE (pSLE). METHODS Fifty-six patients with pSLE, divided into three groups (pre-pubertal, peripubertal and post-pubertal onset), were studied. The SDI (SLICC/ACR Damage Index for SLE), patients' characteristics, disease manifestations and treatments were compared using Fishe...

The paper focuses on anatomical varieties of developmental anomalies of female vagina’s outlet, emphasizing the role of their early recognition in preventing retrograde menstruation by surgical treatment at the beginning of puberty. Three different types of vaginal outlet obstruction are described: imperforate hymen from the group of hymen misdevelopment, transversal vaginal septum from the gro...

IntroductionPrepubertal vaginal bleeding outside the neonatal period is always abnormal and very alarming to both parents physicians. The variable etiologies of vulvovaginitis are most common causes during prepubertal period.We report a series three cases observed „covid“ 2020-2022.Case reporttwo patients 8 9 year -old girls, were refered pediatric secondary center due external bleeding. Hormon...

The aim of the study was to assess age-related changes in sagittal jaw relationship during pre-pubertal and pubertal development on the basis of angular [ANB, anteroposterior dysplasia indicator (APDI) and A-B plane angle] and linear (Wits, AF-BF, App-Bpp, and App-Pgpp) measurements. Lateral cephalograms of orthodontically untreated subjects were evaluated at 7, 9, 11, 13 and 15 years of age. C...

Abstract In a limited resource cow-calf operation, obtaining puberty in heifers is one of the main concerns for long-term productivity. Although nutritional factors have large role heifer development, environmental are sometimes overlooked until catastrophic event such as hurricane occurs. For this project, two groups, born same herd at different intervals, were compared: Group 1(experienced 3r...

· For pre-pubertal children, and certainly for toddlers, adrenal tumors (e.g. adenoma, carcinoma, or bilateral hyperplasia) are a more common cause of CS. In older children, pituitary adenomas are a more common cause of CS. Ectopic (a site other than pituitary or adrenal) sources of CS are extremely rare in children.Overall, there is a female to male predominance, which decreases with younger age.

Prevalence of anti Rubella antibodies was determined using ELISA technique. Seventy seven percent pregnant and 51% pre-pubertal females showed evidence of immunity against rubella while 23% pregnant females were susceptible to rubella infection. There is a need to start rubella immunization programme for girls, to lower the incidence of congenital Rubella (JPMA 37: 6, 1987).

Blood spots taken by finger prick collected on filter paper cards can provide an option to venous blood extraction in monitoring 17-OHP levels in children with Congenital Adrenal Hyperplasia (CAH). This study was done to evaluate the usefulness of blood spot 17-OHP in monitoring disease control in pre-pubertal children with CAH, to correlate it with simultaneously extracted venous 17-OHP levels...