Subconjunctival and subscleral fibrosis are the major causes of failure of filtering surgery. Antiproliferative agents have been successfully used to improve the long-term success of this surgery. Recent advancement in the field of glaucoma surgery has been the use of bioengineered, biodegradable, porous collagen-glycosaminoglycan matrix implant in the subconjunctival and/or subscleral space to...

PURPOSE To compare outcomes in exfoliation glaucoma versus primary open-angle glaucoma (POAG) after ab interno trabeculectomy alone (Trabectome) or in combination with cataract surgery and intraocular lens (IOL) implantation. SETTING Trabectome Study Group institutions. DESIGN Prospective nonrandomized cohort study. METHODS Outcomes included intraocular pressure (IOP), glaucoma medication...

To evaluate the possible postoperative outflow from the anterior chamber of the eye after filtration surgery, a mathematical model based on fluid mechanical principles and clinical data is proposed. Two ophthalmic surgical procedures, non-penetrating deep sclerectomy and trabeculectomy, were analyzed. Based on mathematical modeling, the amount of postoperative outflow through the fistula (after...

PURPOSE To report the occurrence of endophthalmitis after trabeculectomy for glaucoma that was treated by vitrectomy without bleb closure and recurred 3 times after an initial clinically inapparent period of about 2 years. METHODS Interventional case report and short review of the pertinent literature. RESULTS A 73-year-old Caucasian female underwent trabeculectomy (without mitomycin) for g...

PURPOSE To study the effects of filtration surgeries (tube and trabeculectomy) on changes in intraocular pressure after a water-drinking test. METHODS In this prospective, non-randomized, comparative clinical study, 30 patients who had tube surgery and 30 age- and sex-matched trabeculectomy patients underwent a water-drinking test. Only one eye of each patient was included. The baseline intra...

The change in intraocular pressure achieved after 98 trabeculectomy operations performed on 70 patients with primary open-angle glaucoma was analysed. The reduction was proportional to the untreated preoperative pressure, and the results indicated that a first trabeculectomy reduced the intraocular pressure to between 16 and 20 mmHg irrespective of its initial level. Cases which required medica...

Ab interno trabeculectomy is one among several recently introduced minimally invasive glaucoma surgeries that avoid a conjunctival incision and full-thickness sclerostomy involved in traditional glaucoma surgery. Ablation of the trabecular meshwork and inner wall of Schlemm's canal is performed in an arcuate fashion via a clear corneal incision, alone or in combination with phacoemulsification ...

BACKGROUND We investigated the outcome of 23-gauge transconjunctival pars plana vitrectomy (23G PPV) for the treatment of vitreoretinal disorder in patients with prior trabeculectomy. METHODS We retrospectively reviewed medical records of 23G PPV in 11 eyes that had functioning filtering blebs after trabeculectomy. The main outcome measures were the visual acuity, intraocular pressure (IOP) a...