Perceptual learning is an implicit form of learning which induces long-lasting perceptual enhancements. Perceptual learning shows intriguing characteristics. For example, a minimal number of trials per session is needed for learning and the interleaved presentation of more than one stimulus type can hinder learning. Here, we show that these and other characteristics of perceptual learning are v...

Purpose: A proper warm-up method can be used as a strategy to improve performance of athletes in various sport fields. The aim of present study was to compare the effect of two traditional and post-activation potentiation warm-up methods on electromyographic variables of lower extremity muscles during squat jump. Methods: Fourteen trained male athletes were randomly performed three different p...

long-term potentiation (ltp) is a process that certain types of synaptic stimulation lead to a long-lasting enhancement in the strength of synaptic transmission. studies in recent years indicate the importance of molecular pathways in the development of memory and learning. tropomyosin receptor kinase b (trkb) is a member of the neurotrophin receptor tyrosine kinase family, that its ligand is b...

introduction: the primary somatosensory cortex has an important role in nociceptive sensory-discriminative processing. altered peripheral inputs produced by deafferentation or by long-term changes in levels of afferent stimulation can result in plasticity of cortex. capsaicin-induced depletion of c-fiber afferents results in plasticity of the somatosensory system. plasticity includes short-term...

background: sodium valproate (vpa), an anticonvalsant drug, has been reported to stimulate viral replication.  a combination therapy with vpa and acyclovir (acv) is used for the treatment of herpesvirus encephalitis, the commonest sporadic encephalitis of viral origin.   objective: to determine a possible interaction between vpa and acv leading to a modification of antiviral activity of acv.   ...

Background Activity-dependent facilitation of pain is functionally linked to plasticity at synapses between peripheral sensory afferents and spinal projection neurons. However, the underlying cellular and molecular mechanisms are not well-understood [1]. We observed that long-term potentiation at these synapses involves a presynaptic mechanism comprising activity-induced decrease in synaptic fa...

Using confocal microscopy in conjunction with microdrop application of Dil, we have imaged and measured individual dendritic spines of living hippocampal CA1 pyramidal neurons in acute brain slices, before and approximately 3 hr after induction of long-term potentiation by chemical means. Statistical analysis of changes in the length of individual spines, and comparison with results of Monte Ca...

It was demonstrated in both in vivo and in vitro experiments on the renal circula tion that dipyridamole produced the potentiation of vascular responses not only to adenosine but also to norepinephrine. The potentiation of these responses was observed when concentrations of dipyridamole were relatively low. As the concentration of dipyridamole was elevated, the potentiation was rather decreased...