Parkinson disease (PD) is a progressive neurodegenerative disorder affecting 1% of people 65 years and older.1 The core symptoms include the motor manifestations of tremor, bradykinesia, and rigidity. Asymmetric onset and response to dopaminergic therapy are typical of idiopathic PD compared with other causes of parkinsonism. As the disease progresses, postural instability, motor fluctuations, ...

  Abstract   Background: Postural instability has been identified as a potential precursor of   falls in elderly subjects. Postural stability in quiet stance is commonly assessed with   center of pressure (COP) measures. The purpose of this study was to determine testretest reliability and minimal detectable change (MDC) for the center of pressure   (COP) measures in the elderly subjects.   Met...

The main clinical features of Parkinson’s disease are tremor, muscular rigidity, akinesia (inability to move), and postural instability. Other features of the disease include changes in gait, mask-like face, micrographia (progressively smaller handwriting), and psychiatric symptoms; depression occurs in 50% of patients over the course of their illness. The diagnosis is made by clinical symptoms...

Parkinson’s disease is an idiopathic, relentlessly progressive, neurologic disorder manifested clinically by tremor, bradykinesia, rigidity, and postural instability. After completing the diagnostic procedure and having verified the need to start drug treatment, we follow the criteria for therapy aimed at maximum benefits with minimal side effects in the short and long term. This paper examines...

Association of Postural Instability With Asymptomatic Cerebrovascular Damage and Cognitive Decline: The Japan Shimanami Health Promoting Program Study Yasuharu Tabara, PhD; Yoko Okada, MD, PhD; Maya Ohara, MD; Eri Uetani, MD, PhD; Tomoko Kido, MD, PhD; Namiko Ochi, MD, PhD; Tokihisa Nagai, MD, PhD; Michiya Igase, MD, PhD; Tetsuro Miki, MD, PhD; Fumihiko Matsuda, PhD; Katsuhiko Kohara, MD, PhD ....

OBJECTIVE Studies indicate that off-loading adherence is low in patients with diabetic foot ulcers (DFUs), which may subsequently delay healing. However, there is little empirical evidence for this relationship or the factors that influence adherence. RESEARCH DESIGN AND METHODS This prospective, multicenter, international study of 79 (46 from the U.K. and 33 the U.S.) persons with type 2 dia...