This case report demonstrates an excellent outcome in a child with acute necrotizing encephalitis that was likely associated the post-infectious SARS-CoV-2. The aim of this is to emphasize early diagnosis and initiation immunotherapy treatment may yield good outcome, particularly use tocilizumab high-dose methylprednisolone. Post immunotherapy, significant neurological improvement seen through ...

avian infectious bronchitis is an acute and highly contagious disease that mainly causes respiratory symptoms in poultry. a number of serotypes and variants of the viral agent with poor cross-protection are the major problem to achieve desired immunity from vaccination. the s1 subunit of s glycoprotein (spike) is the major determinant of ibv so that a minor change in amino acid sequence of this...

herpes simplex virus accounts for 10 to 25% of sporadic viral encephalitis throughout the world among people of different age with two peaks, one at 5 to 30 and the other at > 50 years of age. pathologic process includes focal brain tissue inflammation and necrosis (predominantly temporal lobe). therefore local neurological signs and symptoms will ensue. although csf pressure rising due to infl...

despite advances in antiviral therapy over the past 2 decades, herpes simplex encephalitis (hse) remains a serious illness with significant risk of morbidity and mortality. hse includes a range of clinical presentations, from aseptic meningitis and fever to a severe rapidly progressive form with mental status changes (clouding of consciousness, confusion, disorientation, personality changes) an...

leptospirosis caused by infection with pathogenic leptospires, which is the most prevalent zoonotic disease in the world. the outer membrane proteins (omps) of pathogenic leptospires such as lipl41 play a crucial role in pathogenesis of this disease. therefore a major challenge to develop an effective vaccine against leptospirosis is application of basic research on the omps of leptospires to i...

BACKGROUND Improvement of additional immunization rate is indicated as an important factor for effective immunization of diseases. In this study, the relationship between retention of mother and child health handbook and additional immunization rate of Japanese encephalitis and tetanus was examined. METHODS A survey via questionnaire was performed against parents of students of middle schools...