نتایج جستجو برای: post transcriptional gene regulation

تعداد نتایج: 1884247  

Journal: :international journal of hematology-oncology and stem cell research 0
shaban alizadeh hematology department, tarbiat modares university, tehran, iran saeid kaviani hematology department, tarbiat modares university, tehran, iran masoud soleimani hematology department, tarbiat modares university, tehran, iran fatemeh kouhkan genetics department, tarbiat modares university, tehran, iran ali akbar pourfathollah immunology department, tarbiat modares university, tehran, iran naser amirizadeh research center of iranian blood transfusion organization (ibto), tehran, iran

background: micrornas (mirna) are small non-coding rnas that have a distinguished role in post- transcriptional gene expression. it’s estimated that 10-30% of human mrnas are regulated by mirnas. many mirnas profiles change during normal erythropoiesis in which some of them are stage specific.mir-155 was downregulated 200 fold in erythropoiesis. materials and methods: k562cells were grown in rp...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Joseph Rodriguez Chih-Hang Anthony Tang Yevgenia L Khodor Sadanand Vodala Jerome S Menet Michael Rosbash

Rhythmic mRNA expression is a hallmark of circadian biology and has been described in numerous experimental systems including mammals. A small number of core clock gene mRNAs and a much larger number of output mRNAs are under circadian control. The rhythmic expression of core clock genes is regulated at the transcriptional level, and this regulation is important for the timekeeping mechanism. H...

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