We determined the prognostic relevance of CD25 (IL-2 receptor-α) expression in 657 patients (≤ 60 years) with de novo acute myeloid leukemia (AML) treated in the Eastern Cooperative Oncology Group trial, E1900. We identified CD25(POS) myeloblasts in 87 patients (13%), of whom 92% had intermediate-risk cytogenetics. CD25 expression correlated with expression of stem cell antigen CD123. In multiv...

This study aimed to explore the associations of occupational stressors (extrinsic effort, reward, and overcommitment), perceived organizational support (POS), and psychological capital (PsyCap) and its components (self-efficacy, hope, resilience, and optimism) with work engagement and the mediating roles of PsyCap and its components among Chinese female nurses within the framework of the job de...

Abstract— In the text books, while solving the circuits with controlled sources using Principle of Superposition (POS), controlled sources are not deactivated. Thus POS has not been applied in the ‘true sense’ to circuits with dependent sources. It is shown here that POS can be applied in the ‘true sense’ to such circuits also, but with caution. POS is applicable to all those circuits with depe...

BACKGROUND Approximately 10% of women suffer from premature ovarian senescence (POS), ca. 9% as occult primary ovarian insufficiency (OPOI, also called premature ovarian aging, POA) and ca. 1% as primary ovarian insufficiency (POI, also called premature ovarian failure, POF). In a large majority of cases POS is currently only diagnosed at advanced clinical stages when women present with clinica...

We investigate the connection between part of speech (POS) distribution and content in language. We define POS blocks to be groups of parts of speech. We hypothesise that there exists a directly proportional relation between the frequency of POS blocks and their content salience. We also hypothesise that the class membership of the parts of speech within such blocks reflects the content load of...

CD4 pos TH1 T cells are considered to play a central role in a number of human autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis. Experimental treatment protocols aimed at selectively eliminating CD4 pos T cells thus far have yielded disappointing clinical results. Here we analyzed phenotype and function of circulating T cells in multiple sclerosis patients treated wi...

CD4(pos) TH1 T cells are considered to play a central role in a number of human autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis. Experimental treatment protocols aimed at selectively eliminating CD4(pos) T cells thus far have yielded disappointing clinical results. Here we analyzed phenotype and function of circulating T cells in multiple sclerosis patients treated ...

This article is focused on the creation of a data model an information system to support processes population sheltering (PoS). PoS have undergone significant changes in Czech Republic. The was transformed for use improvised shelters. For sustainable PoS, it necessary standardize approach crisis management staff. Key research hypotheses: must respect methodological framework planning and implem...