BACKGROUND Recent reports have shown that patients with vascular tumour invasion who undergo concurrent vascular resection can achieve long-term survival rates equivalent to those without vascular involvement requiring pancreaticoduodenectomy alone. There is no consensus about which patients benefit from the portal-superior mesenteric vein resection and there is no consensus about the best surg...

BACKGROUND Circulating miRNA-34a is increased in blood of patients with different liver diseases when compared to healthy controls. However, the origin of miRNA-34a and its possible relationship with hemodynamics and outcome in cirrhotic patients with portal hypertension is unknown. We analyzed the levels of miRNA-34a in cirrhotic patients with severe portal hypertension. METHODS We included ...

In patients with pancreatic head cancer, tumor invasion of the portal vein (PV) or superior mesenteric vein (SMV) is common because of the close anatomical relationship of the pancreatic head and uncinate process to the venous portal system. Pancreatoduodenectomy (PD) with portal vein or superior mesenteric vein resection is well accepted for pancreatic head cancer because of the improvement in...

Objective: To investigate pathological alterations in morphologies of the portal vein, hepatic artery, and hepatic vein in patients with liver cirrhosis and portal hypertension (PHT), to study inducible nitric oxide synthase (iNOS) expression in the hepatic artery wall, and to explore roles of iNOS in pathogenetic mechanisms of portal hypertensive vasculopathy. Methods: Sections of the portal v...

A 39-y-old man, who had an episode of pancreatic bleeding due to chronic pancreatitis, received total pancreatectomy with islet autotransplantation (TP with IAT). Intraoperative ultrasound (US) examination was done to detect transplanted islets and evaluate the quality of US imaging. Islet isolation from the resected total pancreas was performed and approximately 230,000 islet equivalents (IE...

BACKGROUND To discuss the role of Liver 3D printing in the treatment of complex massive hepatocarcinoma with rare variations of portal vein. METHODS Data of enhanced computed tomography (CT) were imported into the medical image three-dimensional visualization system (MI-3DVS) to create Standard Template Library (STL) files, which were read by 3D printer to construct life-size 3D physical live...

Methods A 35-year-old G3P1 patient, referred to our division of Maternal Fetal Medicine at 29 weeks of gestation due to fetal growth retardation. On the first examination, she was afebrile (36. 6’ C), and had normal blood pressure (100/70 mmHg). Past medical or family history revealed no significance and she had no drug, alcohol or tobacco use. Mild cardiomegaly, splenomegaly and dilatation of ...

Antecedent hypoglycemia leads to impaired counterregulation and hypoglycemic unawareness. To ascertain whether antecedent portal vein hypoglycemia impairs portal vein glucose sensing, thereby inducing counterregulatory failure, we compared the effects of antecedent hypoglycemia, with and without normalization of portal vein glycemia, upon the counterregulatory response to subsequent hypoglycemi...

Cell migration or trafficking is an integral aspect of cancer metastasis and is a target for development of novel antimetastatic therapy. Tumor cell trafficking has been a poorly understood phenomenon due to the inability to visualize the process. In this study, we visualized the trafficking of metastatic cells targeting the liver via the portal vein using green fluorescent protein (GFP)-expres...

Cases of liver abscess complicated by portal vein thrombosis are relatively rare. We report a case of liver abscess caused by α-hemolytic streptococci and complicated by portal vein thrombosis. A 51-year-old male presented with fever and right hypochondralgia. He had watery diarrhoea and bloody stool for over 1 month before presentation. Laboratory tests showed elevated hepatobiliary enzymes, i...