Various studies have demonstrated an association between chronic bacterial infections and atherosclerotic cardiovascular disease. Porphyromonas gingivalis, which can invade endothelial cells, is one pathogen that may link these disorders. If so, antibiotics that block its invasiveness may ameliorate atherosclerotic plaque progression. To explore the role of invasion of P. gingivalis in inflamma...

Pendahuluan: Obat kumur herbal banyak dikembangkan karena memiliki sifat antibakteri. Halitosis merupakan bau nafas tidak sedap yang berasal dari oral. Volatile sulfur compounds (VSCs) hasil produksi aktivitas bakteri oral, oleh anaerob gram negatif, salah satunya yaitu Porphyromonas gingivalis menyebabkan halitosis. Flavonoid berpotensi sebagai antioksidan dan mempunyai antibakteri, anti infla...

There are only few studies on the antibacterial activity of red fruit extract (Pandanus conoideus Lam) against oral pathogenic bacteria. Thus, this study aims to determine effectiveness extracts by looking at Minimum inhibitory Concentrations (MIC) and Minimal Bactericidal (MBC) periodontal The subjects were Streptococcus mutans (ATCC 25175), Fusobacterium nucleatum 25586), Porphyromonas gingiv...

A mutual symbiotic enhancement of growth of Porphyromonas gingivalis and Treponema denticola is described in this report. Brain heart infusion broth supplemented with vitamin K did not support the individual growth of P. gingivalis or T. denticola. However, when inoculated as a mixture, both bacterial species did grow significantly. The growth-stimulating factors produced by P. gingivalis and T...

Bacteroides (Porphyromonas) gingivalis and Bacteroides (Porphyromonas) intermedius have been implicated in the etiology of human periodontal diseases. These organisms are able to bind and degrade human fibrinogen, and these interactions may play a role in the pathogenesis of periodontal disease. In attempts to map the bacterial binding sites along the fibrinogen molecule, we have found that str...

Purpose The aim of this study was to evaluate the ability of Porphyromonas gingivalis (P. gingivalis) to induce oxidation of high-density lipoprotein (HDL) and to determine whether the oxidized HDL induced by P. gingivalis exhibited altered antiatherogenic function or became proatherogenic. Methods P. gingivalis and THP-1 monocytes were cultured, and the extent of HDL oxidation induced by P. ...