نتایج جستجو برای: porphyromonas

تعداد نتایج: 3941  

Journal: :The Journal of biological chemistry 2003
Jowita Mikolajczyk Kelly M Boatright Henning R Stennicke Tamim Nazif Jan Potempa Matthew Bogyo Guy S Salvesen

Most proteases are synthesized as inactive precursors to protect the synthetic machinery of the cell and allow timing of activation. The mechanisms used to render latency are varied but tend to be conserved within protease families. Proteases belonging to the caspase family have a unique mechanism mediated by transitions of two surface loops, and on the basis of conservation of mechanism one wo...

Journal: :Journal of immunology 2007
Katarzyna Popadiak Jan Potempa Kristian Riesbeck Anna M Blom

Periodontitis is an inflammatory disease of the supporting structures of the teeth and is caused by, among other agents, Porphyromonas gingivalis. P. gingivalis is very resistant to killing by human complement, which is present in a gingival fluid at 70% of the serum concentration. We found that the incubation of human serum with purified cysteine proteases of P. gingivalis (gingipains) or P. g...

2014
Dali Liu Yanbin Zhou Mariko Naito Hiromichi Yumoto Qiang Li Yoichiro Miyake Jingping Liang Rong Shu

Porphyromonas gingivalis strain SJD2 was isolated from subgingival plaque of a patient in China with chronic periodontitis. Here, we report the draft genome of this strain, with a size of 2,328,850 bp, average G+C content of 48.3%, and 2,020 predicted protein-coding sequences.

Journal: :Anaerobe 2012
Gerusa N A Senhorinho Viviane Nakano Chengxu Liu Yuli Song Sydney M Finegold Mario J Avila-Campos

The occurrence of Porphyromonas gulae, Porphyromonas macacae, Fusobacterium nucleatum and Fusobacterium canifelinum in subgingival plaque from dogs with and without periodontitis as well as their antimicrobial susceptibility were evaluated. From 50 dogs with periodontitis were identified 38 P. gulae, 8 P. macacae, 26 F. nucleatum and 15 F. canifelinum, and from 50 dogs without periodontitis wer...

2016
Cristiane GONÇALVES Geisla Mary S. SOARES Marcelo FAVERI Paula Juliana PÉREZ-CHAPARRO Eduardo LOBÃO Luciene Cristina FIGUEIREDO Gustavo Titonele BACCELLI Magda FERES

Objective The aim of this study was to evaluate the association of Porphyromonas endodontalis, Filifactor alocis and Dialister pneumosintes with the occurrence of periodontitis. Material and Methods Thirty subjects with chronic periodontitis (ChP) and 10 with periodontal health (PH) were included in the study. Nine subgingival biofilm samples were collected as follows: i) PH group - from the me...

Journal: :Brazilian dental journal 2003
Luciana Moura Sassone Rivail Antonio Sergio Fidel Sandra Rivera Fidel Marina Dias Raphael Júnior Hirata

The purpose of this study was to analyze the in vitro antimicrobial activity of sodium hypochlorite (1% and 5%) and chlorhexidine (0.12%, 0.5% and 1%). Bacterial samples (ATCC) of Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Porphyromonas gingivalis and Fusobacterium nucleatum were submitted to a contact test. Solutions were evaluated at different time intervals: immediately,...

2017
Wilson Bautista-Molano Desirée van der Heijde Robert Landewé Gloria I Lafaurie Juliette de Ávila Rafael Valle-Oñate Consuelo Romero-Sanchez

Objective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluation of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease-modifying antirheumatic drug (bDMARD) naive fulfilling the Assessment of SpondyloArthritis in...

2015
Camille Zenobia George Hajishengallis

The oral bacterium Porphyromonas gingivalis has special nutrient requirements due to its asaccharolytic nature subsisting on small peptides cleaved from host proteins. Using proteases and other virulence factors, P. gingivalis thrives as a component of a polymicrobial community in nutritionally favorable inflammatory environments. In this regard, P. gingivalis has a number of strategies that su...

2015
Ingar Olsen Ann Progulske-Fox

Porphyromonas gingivalis is considered a major pathogen in adult periodontitis and is also associated with multiple systemic diseases, for example, cardiovascular diseases. One of its most important virulence factors is invasion of host cells. The invasion process includes attachment, entry/internalization, trafficking, persistence, and exit. The present review discusses these processes related...

2011
Ulvi Kahraman Gursoy Eija Könönen Pirkko J. Pussinen Taina Tervahartiala Kati Hyvärinen Anna L. Suominen Veli-Jukka Uitto Susanna Paju Timo Sorsa

In the present study, we propose a novel diagnostic approach, using 3 different salivary markers, representing periodontal pathogen burden, inflammation, and tissue degradation, for detecting periodontitis. The salivary concentrations of Porphyromonas gingivalis, interleukin-1β, and matrix metalloproteinase-8, available from salivary specimens of 165 subjects (84 subjects with advanced periodon...

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