BACKGROUND Immunohistochemical staining for cluster designation 5 (CD5) has been found to label a variety of non-lymphoid tumors. METHODS A variety of eccrine, apocrine, follicular, epithelial, and pagetoid lesions were selected and stained with an anti-CD5 monoclonal antibody (Novocastra Labs, Newcastle upon Tyne, UK, clone 4C7) by immunohistochemistry. The intensity of positive cytoplasmic ...

Desmoplastic melanocytic nevi can be difficult to distinguish from desmoplastic melanoma. The presence of lymphocytic aggregates in association with a sclerosing melanocytic proliferation is commonly regarded as a feature in support of a diagnosis of desmoplastic melanoma. However, the finding is not specific for melanoma. Herein we report six cases of sclerosing melanocytic nevi with associate...

A 40-year-old patient presented with a papule on the calf with irregular brown pigmentation (Figure 1). On dermatoscopy the lesion was composed of segmental radial lines and structureless zones. Discrete reticular lines were also seen but they were also present in the surrounding normal skin. The pigmentation did not extend towards the edge of the visible scar. Disregarding the clinical history...

Nevus of Ota (oculodermal melanosis) is a dermal melanocytic hamartoma with bluish hyperpigmentation along the first and second branches of the trigeminal nerve. Extracutaneous involvement, especially ocular, has been reported. A 45-year-old male presented with malignant melanoma of the left orbit in association with nevus of Ota. Being locally invasive, a modified exenteration with frontal fla...

Pigmented lesions of the cervix are a rarity. Blue nevus occurs as an incidental finding in cervix in hysterectomy specimens from middle aged women. This condition is more appropriately called ‘Focal Stromal Melanocytosis” as the findings are more analogous to dermal melanocytosis rather than to cutaneous blue nevi. There are only a couple of reports of cervical blue nevi in the Indian literatu...

We report a 2-year-old girl with developmental delay who, from the age of 1 year, developed perniotic lesions of the hands and feet initially diagnosed as chilblain lupus. Histological examination showed features of epidermal necrosis with intraepidermal bulla formation, interface dermatitis, lymphocytic vasculitis with fibrinoid necrosis and thrombi formation, both superficial and deep dermal ...

Introduction: Nevus sebaceous (NS) is a hamartoma composed of epidermal, dermal, follicular, and apocrine appendages found in the pediatric population. The current standard treatment full-thickness excision, but this controversial as much still unknown about malignant potential benign neoplasm. Secondary lesions associated with nevus include poromas, trichoblastomas, syringocystadenomas. purpos...

Dermoscopy revealed a well-defined, erythematous-pink tumor (Fig. 2A) with prominent, more or less evenly distributed blood vessels, with characteristic cherry blossom images mostly at the periphery of the tumor (Fig. 2B), and pale pink structureless areas (Fig. 2A). With a suspected diagnosis of eccrine poroma, the lesion was excised and the histological findings confirmed the diagnosis. Eccri...

Dermoscopy revealed a well-defined, erythematous-pink tumor (Fig. 2A) with prominent, more or less evenly distributed blood vessels, with characteristic cherry blossom images mostly at the periphery of the tumor (Fig. 2B), and pale pink structureless areas (Fig. 2A). With a suspected diagnosis of eccrine poroma, the lesion was excised and the histological findings confirmed the diagnosis. Eccri...

Eccrine porocarcinoma is a rare malignant adnexal tumor of ductal portion of eccrine sweat gland. It occurs commonly in the lower extremities and rarely in scalp, face, ear, trunk and upper extremities. This survey presents a classic case of eccrine porocarcinoma of scalp in a 58 yr old male patient, presenting as cauliflower like growth over parietal aspect of scalp.