BACKGROUND Compromised receptivity of the endometrium is a major cause of unexplained infertility, implantation failure and subclinical pregnancy loss. In order to investigate the changes in endometrial protein profile as a cause of unexplained infertility, the current study was undertaken to analyze the differentially expressed proteins of endometrium from early-secretory (LH+2) to mid-secreto...

The purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. Specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. ...

HEALTH ISSUE: In Canada, cancers of the endometrium, ovaries, vulva, vagina, placenta and adnexa account for 11% of all malignant neoplasms in women and 81% of all genital cancers. Although the incidence and mortality from vulvar and vaginal cancers are very low, endometrium and ovarian cancer are important public health problems. KEY FINDINGS: In Canada, there has been no appreciable improveme...

The objective of this prospective follow-up study was to evaluate the potential utility of three-dimensional (3D) ultrasound to differentiate intrauterine from extrauterine gestations. Fifty-four pregnancies with a gestational age <10 weeks and with an intrauterine gestational sac <5 mm in diameter formed the study group. The configuration of the endometrium in the frontal plane of the uterus w...

1 (Demonstrator, Department of Pathology, Medical College, Kolkata-73, WBUHS, India) 2 (Professor, Department of Pathology, Malda Medical College, Malda, WBUHS, India) 3 (Assistant Director of Medical Education, Swasthya Bhawan, Kolkata-91, India) 4 (Senior Resident, Chittaranjan National cancer Institute, Kolkata-26, India) 5 (Assistant Professor, Department of Obstretics & Gynaecology, KPC Me...

BACKGROUND Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. CASE STUDY A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the neoplasm exhibited positive immunoreactivity for synaptophysin, pancytokeratin and CD56 but was n...

Pregnancy rates are low and litter sizes generally small when assisted reproduction techniques are used in gonadotropin-treated felid (cat) species. A prerequisite to determining whether or not abnormal morphological changes in the uterine lumen or corpus luteum (CL) are related to this reproductive failure is the documentation of normal histological kinetics during natural embryogenesis. This ...

background: aggressive embryo and receptive endometrium are necessary for successful implantation. on this time endometrium transformates to receptive state, which permits embryonic implantation. studies about embryonic implantation and endometrial receptivity are always a hot spot in the field of reproductive medicine. objective: to investigate the expression pattern of meis1 during peri-impla...