BACKGROUND While we have international guidelines and various national guidelines for asthma diagnosis and management, asthma remains poorly controlled in many children and adults. In this paper we review the limitations of current asthma guidelines and describe important issues and remaining questions regarding asthma guidelines for use, particularly in primary care. DISCUSSION Clinical prac...

Asthma represents a profound worldwide public health problem. The most effective anti-asthmatic drugs currently available include inhaled beta2-agonists and glucocorticoids and control asthma in about 90-95% of patients. The current asthma therapies are not cures and symptoms return soon after treatment is stopped even after long term therapy. Although glucocorticoids are highly effective in co...

Original Research F patients with asthma who remain uncontrolled despite inhaled corticosteroid (ICS) therapy, a longacting inhaled b 2 -agonist (LABA) may be added. 1,2 Combination therapy improves symptoms, reduces severe exacerbation rate and achieves better asthma control in more patients than ICS monotherapy. 1,3-5 However, poor adherence to bid therapy may account for poor asthma control ...

Asthma is a complicated disorder, whose prevalence has increased over the past few decades.Asthma is characterized by infiltration of inflammatory leukocytes along with enhancedproinflammatory cytokines and chemokines. Fungi are now far more widely being considered as thedominant extrinsic trigger for asthma. Fungi are linked to the severity of asthma in many ways. Somedifferences between studi...

BACKGROUND Non-eosinophilic asthma is a potentially important clinicopathological phenotype since there is evidence that it responds poorly to inhaled corticosteroid therapy. However, little is known about the underlying airway immunopathology and there are no data from placebo-controlled studies examining the effect of inhaled corticosteroids. METHODS Airway immunopathology was investigated ...

BACKGROUND The measurement of health-related quality of life (HRQoL) is increasingly recognized as an important endpoint, as a reflection of the effects of the disease from a patient perspective. Our aim was to evaluate the factors determining the HRQoL in patients with asthma, according to the EQ-5D questionnaire. METHODS Patients were included using multi-stage sampling, from Primary Care c...

asthma is a complicated disorder, whose prevalence has increased over the past few decades.asthma is characterized by infiltration of inflammatory leukocytes along with enhancedproinflammatory cytokines and chemokines. fungi are now far more widely being considered as thedominant extrinsic trigger for asthma. fungi are linked to the severity of asthma in many ways. somedifferences between studi...

At present, asthma represents a substantial burden on health care resources in all countries so far studied. The costs of asthma are largely due to uncontrolled disease, and are likely to rise as its prevalence and severity increase. Costs could be significantly reduced if disease control is improved. A large proportion of the total cost of illness is derived from treating the consequences of p...

Abstract Introduction Asthma is a respiratory disease caused by chronic airway inflammation in the lungs that constricts and increases mucus production.1 considered most common of people living Kuwait.2 Pharmacists can play key roles to support optimal health outcomes for patients with asthma. However, there limited evidence describing pharmacists’ experiences asthma treatment primary care cent...