ZnO nano-particles is synthesized using hydrated zinc chloride (ZnCl2.2H2O) as main raw components. It calcined at different temperatures (i.e., 200 ⁰C, 400 ºC, 600 ⁰C and 800 ⁰C). Synthesized characterized by XRD, SEM/EDS, HRTEM, UV Visible, Band Gap. XRD result showed pure wurtzite-structure crystalline nature. Both results SAED obtained from pattern HRTEM studies are indicated similar inform...

Objective(s): Drug delivery is an engineering technology to control the release and delivery of therapeutic agents to target organs, tissues, and cells. Metallic nanoparticles, such as gold nanoparticles (AuNPs) have exceptional properties which enable efficient drug transport into different cell types with reduced side effects and cytotoxicity to other tissues.Materials and Methods: AuNPs were...

Investigations on the dose response of cell fusion, induced by ionfree aqueous polyethylene glycol (PEG) solutions, reveal distinct lowest fusogenic PEG concentrations for different permanently growing mammalian cell lines. Part of the requisite PEG can be replaced by carbohydrates, preserving the fusogenity of the solutions. This discriminates two effects of PEG solutions causing cell fusion: ...

Triple-negative breast cancer (TNBC) lacks effective treatment options due to the absence of traditional therapeutic targets. The epidermal growth factor receptor (EGFR) has emerged as a promising target for TNBC therapy because it is overexpressed in about 50% of TNBC patients. Here we describe a PEG engager that simultaneously binds polyethylene glycol and EGFR to deliver PEGylated nanomedici...

Polyethylene glycols (PEGs) are products of condensed ethylene oxide and water that can have various derivatives and functions. Since many PEG types are hydrophilic, they are favorably used as penetration enhancers, especially in topical dermatological preparations. PEGs, together with their typically nonionic derivatives, are broadly utilized in cosmetic products as surfactants, emulsifiers, c...

Feedstock for powder injection moulding of silver was prepared using water-soluble binder composed polyethylene glycol (PEG) and polyvinyl butyrol (PVB). Silver powders with particle size in range 1 μm to 20 can be mixed PEG/PVB system form feedstocks having loadings 42 vol% 45 vol%. PEG removed water leaching method while PVB by thermal debinding. Specimens retained their shapes during debindi...

The preclinical development of peptidyl drugs for cancer treatment is hampered by their poor pharmacologic properties and cell penetrative capabilities in vivo. In this study, we report a nanoparticle-based formulation that overcomes these limitations, illustrating their utility in studies of the anticancer peptide NuBCP-9, which converts BCL-2 from a cell protector to a cell killer. NuBCP-9 wa...

The objective of this work was to produce brushite cement for orthopedic applications, based on the system wollastonite/phosphoric acid with incorporation polyethylene glycol (PEG) as a setting and processing additive. Brushite/PEG obtained by dissolution-precipitation method its physicochemical properties were characterized X-ray diffraction, compressive strength, porosimetry, biological behav...

In this work, blends of polyethylene glycol (PEG) and poly(methyl methacrylate) (PMMA) with nanosponge-like porous structure are fabricated by a solution phase separation method, subsequently the nanosponge-porous also applied for high performance triboelectric nanogenerator (TENG). The features controlled varying polymer concentrations PEG/PMMA ratios. A TENG device made PEG-PMMA blend convex-...