نتایج جستجو برای: polycystic kidney disease

تعداد نتایج: 1627416  

Journal: :Journal of the American Society of Nephrology 2015

2015
CA Stănescu DN Păduraru C Cirimbei E Brătucu

The hepatic polycystic disease represents a hereditary condition with a reduced prevalence in the general population, sometimes associated with polycystic kidney disease. We present a retrospective observational study applied to 49 patients. The study aimed to observe the laparoscopic surgery of simple hepatic cysts. Laparoscopic approach is a simple and successful surgery management of these t...

Journal: :Gastroenterology 2009
Loes van Keimpema Frederik Nevens Ragna Vanslembrouck Martijn G H van Oijen Aswin L Hoffmann Helena M Dekker Robert A de Man Joost P H Drenth

BACKGROUND & AIMS Therapy for polycystic liver is invasive, expensive, and has disappointing long-term results. Treatment with somatostatin analogues slowed kidney growth in patients with polycystic kidney disease (PKD) and reduced liver and kidney volume in a PKD rodent model. We evaluated the effects of lanreotide, a somatostatin analogue, in patients with polycystic liver because of autosoma...

2010
Hannah C. Chapin Michael J. Caplan

Polycystic kidney disease is a common genetic disorder in which fluid-filled cysts displace normal renal tubules. Here we focus on autosomal dominant polycystic kidney disease, which is attributable to mutations in the PKD1 and PKD2 genes and which is characterized by perturbations of renal epithelial cell growth control, fluid transport, and morphogenesis. The mechanisms that connect the under...

2017
Holly Mabillard Shalabh Srivastava Philip Haslam Maciej Karasek John A Sayer

The complications of autosomal dominant polycystic kidney disease (ADPKD) include cyst rupture and haemorrhage leading to loin pain and frank haematuria. Risk factors include large kidney volume, hypertension, and renal impairment. We present a case of a young male who, following trauma to the kidney, had a life threatening bleed from his polycystic kidney. The case was initially treated with f...

Journal: :Kidney International Reports 2021

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disorder (estimated prevalence of 1 per 1000–1 2500 live births)1 characterized by development and growth multiple bilateral cysts eventually leading to end-stage renal replacement therapy.1

 فرخ لقا احمدی, , اعظم سلیمانی, , بهزاد عین الهی, , سپیده سیفی, , سیما مازیار, , محبوب لسان پزشکی, , محمدرضا خاتمی, , میترا مهدوی مزده, ,

Background: Autosomal-dominant polycystic kidney disease (ADPKD), a common hereditary disease, is characterized by the progressive development and enlargement of multiple cysts in both kidneys, and typically resulting in end stage renal disease (ESRD) by the fifth decade of life. Post-transplant diabetes mellitus (PTDM), a common complication after transplantation with an incidence rate of 2.5-...

Journal: :Circulation 2014
Wissam A Aboualaiwi Brian S Muntean Shobha Ratnam Bina Joe Lijun Liu Robert L Booth Ingrid Rodriguez Britney S Herbert Robert L Bacallao Marcus Fruttiger Tak W Mak Jing Zhou Surya M Nauli

BACKGROUND Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease, a cilia-associated pathology (ciliopathy). Survivin overexpression is associated with cancer, but the clinical pathology associated with survivin downregulation or knockout has never been studied before. The present studies aim to examine whether and how cilia function (...

2006
Muthukumar Kannabiran Vinod Singh Sandeep Grewal

Objective: To describe a rare case of Acromegaly presenting as psychotic disorder in a woman with familial autosomal dominant polycystic kidney disease (ADPKD). Method: Single case report. Results: We describe the case of a 50 year old woman, who presented with an acute psychotic episode. She had polycystic disease of kidney and liver and family history of polycystic disease. She presented with...

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