نتایج جستجو برای: polyclonal

تعداد نتایج: 11955  

Journal: :Proceedings of the National Academy of Sciences 1993

Journal: :Cancer research 2004
William C Kisseberth Eric P Sandgren

Studies of cellular interactions are critical to the understanding of tumorigenesis. Although many studies have demonstrated a monoclonal composition of advanced neoplasms in humans and mice, the clonal composition of smaller, antecedent lesions has been studied less thoroughly. To examine the clonal development of breast cancer, we generated chimeric mammary glands using mouse mammary epitheli...

2017
Kourosh Maboudi Seyedeh Marzieh Hosseini Mina Sepahi Hashem Yaghoubi Shahin Hadadian

BACKGROUND Erythropoietin, as a principal hormone promotes red blood cell production in bone marrow. Varieties of erythropoietin biosimilar are being produced by recombinant DNA technology in cell cultures. The detection or quantifi cation of these molecules are being performed by diff erent methods which some of theme such as Western blot and enzymelinked immunosorbent assay (ELISA) require sp...

Journal: :Annals of the rheumatic diseases 1990
P Barbieri I Olivieri G Benedettini P Marelli M L Ciompi G Pasero M Campa

The peripheral blood lymphocyte response of patients with ankylosing spondylitis (AS) to several polyclonal B cell activators was investigated. No differences were found in the reactivity to pokeweed mitogen and protein A between patients and controls; in contrast, the peripheral blood lymphocyte response to Staphylococcus aureus strain Cowan I (SAC) was significantly higher in patients with AS...

2013
Charles Mackworth-Young Jorge Sabbaga

We investigated idiotypic markers of monoclonal antibodies derived from patients with polyclonal B-cell activation. Four monoclonal antibodies with different ligand binding specificities derived from a patient with lepromatous leprosy and three monoclonal anti-DNA antibodies from two patients with SLE were studied. Three new public idiotopes, which were common to monoclonal antibodies from all ...

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